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Bis(5'- nucleosyl)- tetraphosphatase [asymmetrical] Nucleoside diphosphate kinase 6 Ectonucleoside triphosphate diphosphohydrolase 5 Ectonucleoside triphosphate diphosphohydrolase 8 Guanylate kinase Nucleoside diphosphate kinase 6 Guanylate kinase Cytosolic purine 5'-nucleotidase Deoxyguanosine kinase Adenine phosphoribosyltransferase Cytosolic purine 5'-nucleotidase Purine nucleoside phosphorylase Hypoxanthine- guanine phosphoribosyltransferase Purine nucleoside phosphorylase Guanine deaminase ADP-sugar pyrophosphatase Ribose- phosphate pyrophosphokinase 1 Amidophosphoribosyltransferase Trifunctional purine biosynthetic protein adenosine-3 Trifunctional purine biosynthetic protein adenosine-3 Phosphoribosylformylglycinamidine synthase Multifunctional protein ADE2 Multifunctional protein ADE2 Adenylosuccinate lyase Bifunctional purine biosynthesis protein PURH Bifunctional purine biosynthesis protein PURH Inosine triphosphate pyrophosphatase GMP synthase [glutamine- hydrolyzing] Inosine-5'- monophosphate dehydrogenase 1 GMP reductase 1 Cytosolic purine 5'-nucleotidase Purine nucleoside phosphorylase Cytosolic purine 5'-nucleotidase Hypoxanthine- guanine phosphoribosyltransferase Purine nucleoside phosphorylase Hypoxanthine- guanine phosphoribosyltransferase Xanthine dehydrogenase/oxidase Xanthine dehydrogenase/oxidase Purine nucleoside phosphorylase Adenylosuccinate synthetase isozyme 2 AMP deaminase 1 Adenylosuccinate lyase Adenosine deaminase Purine nucleoside phosphorylase Purine nucleoside phosphorylase Adenosine deaminase Adenine phosphoribosyltransferase Ectonucleoside triphosphate diphosphohydrolase 5 Adenylate kinase isoenzyme 1 ATPase family AAA domain- containing protein 1 cAMP-specific 3',5'-cyclic phosphodiesterase 4D Adenylate kinase isoenzyme 1 Cytosolic purine 5'-nucleotidase Nucleoside diphosphate kinase 6 Guanylate cyclase cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Ectonucleoside triphosphate diphosphohydrolase 8 Inosine triphosphate pyrophosphatase Nucleoside diphosphate kinase 6 Ectonucleoside triphosphate diphosphohydrolase 8 Adenine phosphoribosyltransferase Trifunctional purine biosynthetic protein adenosine-3 Thioredoxin Thioredoxin Ribonucleoside- diphosphate reductase large subunit Ribonucleoside- diphosphate reductase subunit M2 Ectonucleoside triphosphate diphosphohydrolase 5 Thioredoxin Thioredoxin Ribonucleoside- diphosphate reductase large subunit Ribonucleoside- diphosphate reductase subunit M2 Phosphoribosyl pyrophosphate Diguanosine tetraphosphate H2O Guanosine triphosphate Guanosine monophosphate Accumulation ATP Guanosine diphosphate Accumulation ADP H2O Guanosine monophosphate Pi H2O Pi Accumulation ATP Accumulation ADP Accumulation ATP dGDP Accumulation ADP dGTP Accumulation ATP 2'-Deoxyguanosine 5'-monophosphate Accumulation ADP H2O Deoxyguanosine Pi Accumulation ATP Accumulation ADP PPi Guanine Phosphoribosyl pyrophosphate H2O Guanosine Pi Pi Ribose 1-phosphate PPi Phosphoribosyl pyrophosphate Pi Deoxyribose 1-phosphate H2O Xanthine NH3 Adenosine diphosphate ribose H2O AMP D-Ribose 5-phosphate Accumulation ATP AMP 5-Phosphoribosylamine PPi L-Glutamic acid L-Glutamine H2O Accumulation ATP Glycine Accumulation ADP Pi Glycineamideribotide 10-Formyltetrahydrofolate Tetrahydrofolic acid 5'-Phosphoribosyl-N- formylglycinamide Accumulation ATP H2O Accumulation ADP Pi Phosphoribosylformylglycineamidine 5-amino-1-(5-phospho-D- ribosyl)imidazole-4- carboxylate 5-Aminoimidazole ribonucleotide CO2 Accumulation ATP L-Aspartic acid Accumulation ADP Pi SAICAR Fumaric acid AICAR 10-Formyltetrahydrofolate Tetrahydrofolic acid Phosphoribosyl formamidocarboxamide Inosinic acid H2O H2O PPi Accumulation ATP Xanthylic acid NH3 AMP PPi NAD H2O NADH NH3 NADP NADPH H2O Xanthosine Pi Pi Ribose 1-phosphate H2O Inosine Pi PPi Phosphoribosyl pyrophosphate Pi Hypoxanthine Ribose 1-phosphate PPi O2 H2O H2O2 NAD H2O Uric acid NADH Deoxyinosine Pi Deoxyribose 1-phosphate GTP L-Aspartic acid GDP Pi Adenylsuccinic acid Adenosine monophosphate H2O NH3 Fumaric acid Accumulation Adenosine H2O NH3 Pi Accumulation Adenine Ribose 1-phosphate Deoxyadenosine Pi Deoxyribose 1-phosphate H2O NH3 PPi Phosphoribosyl pyrophosphate Accumulation Adenosine diphosphate H2O Pi Accumulation Adenosine triphosphate H2O Pi cAMP H2O PPi Accumulation ATP Deoxyadenosine monophosphate Accumulation ADP dADP H2O Pi Accumulation ATP Accumulation ADP Accumulation Deoxyadenosine triphosphate Guanosine 2',3'-cyclic phosphate PPi H2O IDP H2O Pi Inosine triphosphate H2O PPi Accumulation ATP Accumulation ADP H2O Pi PPi 5-Aminoimidazole-4-carboxamide Phosphoribosyl pyrophosphate Accumulation ATP Accumulation ADP Pi H2O Pi H2O H2O Magnesium Calcium Magnesium Calcium Magnesium Magnesium Magnesium Magnesium Zinc (II) ion Magnesium Magnesium Magnesium Potassium Magnesium Magnesium Magnesium Magnesium FAD FAD Magnesium Zinc (II) ion Zinc (II) ion Zinc (II) ion Calcium Magnesium Zinc (II) ion Magnesium Magnesium Heme Zinc (II) ion Magnesium Calcium Magnesium Magnesium Calcium Disulfide Fe3+ Calcium Magnesium Disulfide Fe3+ Pentose Phosphate Pathway Endoplasmic Reticulum Peroxisome Endoplasmic Reticulum Peroxisome Intracellular Space Extracellular Space Mitochondria
Nudt2 Nme6 Entpd5 Entpd8 Guk1 Nme6 Guk1 Nt5c2 Dguok Aprt Nt5c2 Pnp Hprt1 Pnp Gda Nudt5 Prps1 Ppat Gart Gart Pfas Paics Paics Adsl Atic Atic Itpa Gmps Impdh1 Gmpr Nt5c2 Pnp Nt5c2 Hprt1 Pnp Hprt1 Xdh Xdh Pnp Adss Ampd1 Adsl Ada Pnp Pnp Ada Aprt Entpd5 Ak1 Atad1 Pde4d Ak1 Nt5c2 Nme6 Gucy1a1 Gucy1b1 Pde10a Entpd8 Itpa Nme6 Entpd8 Aprt Gart Txn Txn Rrm1 Rrm2 Entpd5 Txn Txn Rrm1 Rrm2 Phosphoribosyl pyrophosphate Diguanosine tetraphosphate Water Guanosine triphosphate Guanosine monophosphate Accumulation Adenosine triphosphate Guanosine diphosphate Accumulation Adenosine diphosphate Water Guanosine monophosphate Phosphate Water Phosphate Accumulation Adenosine triphosphate Accumulation Adenosine diphosphate Accumulation Adenosine triphosphate dGDP Accumulation Adenosine diphosphate dGTP Accumulation Adenosine triphosphate 2'- Deoxyguanosine 5'- monophosphate Accumulation Adenosine diphosphate Water Deoxyguanosine Phosphate Accumulation Adenosine triphosphate Accumulation Adenosine diphosphate Pyrophosphate Guanine Phosphoribosyl pyrophosphate Water Guanosine Phosphoric acid Phosphate Ribose 1-phosphate Pyrophosphate Phosphoribosyl pyrophosphate Phosphate Deoxyribose 1-phosphate Water Xanthine Ammonia Adenosine diphosphate ribose Water Adenosine monophosphate D-Ribose 5-phosphate Accumulation Adenosine triphosphate Adenosine monophosphate 5- Phosphoribosylamine Pyrophosphate L-Glutamic acid L-Glutamine Water Accumulation Adenosine triphosphate Glycine Accumulation Adenosine diphosphate Phosphate Glycineamideribotide 10- Formyltetrahydrofolate Tetrahydrofolic acid 5'- Phosphoribosyl- N- formylglycinamide Accumulation Adenosine triphosphate Water Accumulation Adenosine diphosphate Phosphoric acid Phosphoribosylformylglycineamidine 5-amino-1-(5- phospho-D- ribosyl)imidazole- 4-carboxylate 5- Aminoimidazole ribonucleotide Carbon dioxide Accumulation Adenosine triphosphate L-Aspartic acid Accumulation Adenosine diphosphate Phosphoric acid SAICAR Fumaric acid AICAR 10- Formyltetrahydrofolate Tetrahydrofolic acid Phosphoribosyl formamidocarboxamide Inosinic acid Water Water Pyrophosphate Accumulation Adenosine triphosphate Xanthylic acid Ammonia Adenosine monophosphate Pyrophosphate NAD Water NADH Ammonia NADP NADPH Water Xanthosine Phosphate Phosphate Ribose 1-phosphate Water Inosine Phosphate Pyrophosphate Phosphoribosyl pyrophosphate Phosphate Hypoxanthine Ribose 1-phosphate Pyrophosphate Oxygen Water Hydrogen peroxide NAD Water Uric acid NADH Deoxyinosine Phosphate Deoxyribose 1-phosphate Guanosine triphosphate L-Aspartic acid Guanosine diphosphate Phosphate Adenylsuccinic acid Adenosine monophosphate Water Ammonia Fumaric acid Accumulation Adenosine Water Ammonia Phosphate Accumulation Adenine Ribose 1-phosphate Deoxyadenosine Phosphate Deoxyribose 1-phosphate Water Ammonia Pyrophosphate Phosphoribosyl pyrophosphate Accumulation Adenosine diphosphate Water Phosphoric acid Accumulation Adenosine triphosphate Water Phosphoric acid cAMP Water Pyrophosphate Accumulation Adenosine triphosphate Deoxyadenosine monophosphate Accumulation Adenosine diphosphate dADP Water Phosphoric acid Accumulation Adenosine triphosphate Accumulation Adenosine diphosphate Accumulation Deoxyadenosine triphosphate Guanosine 2',3'-cyclic phosphate Pyrophosphate Water IDP Water Phosphate Inosine triphosphate Water Pyrophosphate Accumulation Adenosine triphosphate Accumulation Adenosine diphosphate Water Phosphate Pyrophosphate 5- Aminoimidazole- 4-carboxamide Phosphoribosyl pyrophosphate Accumulation Adenosine triphosphate Accumulation Adenosine diphosphate Phosphate Water Phosphate Water Water Pentose Phosphate Pathway
Nudt2 Nme6 Entpd5 Entpd8 Guk1 Nme6 Guk1 Nt5c2 Dguok Aprt Nt5c2 Pnp Hprt1 Pnp Gda Nudt5 Prps1 Ppat Gart Gart Pfas Paics Paics Adsl Atic Atic Itpa Gmps Impdh1 Gmpr Nt5c2 Pnp Nt5c2 Hprt1 Pnp Hprt1 Xdh Xdh Pnp Adss Ampd1 Adsl Ada Pnp Pnp Ada Aprt Entpd5 Ak1 Atad1 Pde4d Ak1 Nt5c2 Nme6 Gucy1a1 Gucy1b1 Pde10a Entpd8 Itpa Nme6 Entpd8 Aprt Gart Txn Txn Rrm1 Rrm2 Entpd5 Txn Txn Rrm1 Rrm2 PRPP Guan2P4 H2O GTP GSMP Accumulation ATP GDP Accumulation ADP H2O GSMP Pi H2O Pi Accumulation ATP Accumulation ADP Accumulation ATP dGDP Accumulation ADP dGTP Accumulation ATP dGMP Accumulation ADP H2O doxyG Pi Accumulation ATP Accumulation ADP PPi Guanine PRPP H2O Guo Pi Pi Rib-1P PPi PRPP Pi D1P H2O Xanthin NH3 ADP-Rib H2O AMP DRib-5P Accumulation ATP AMP 5-PPRSA PPi Glu Gln H2O Accumulation ATP Gly Accumulation ADP Pi Glyadbt 10-FTHF THFA 5PPNFG Accumulation ATP H2O Accumulation ADP Pi FGAM CR 5-AnRbn CO2 Accumulation ATP Asp Accumulation ADP Pi SAICAR Fumarat AICAR 10-FTHF THFA FosbFca Imp H2O H2O PPi Accumulation ATP XntylcA NH3 AMP PPi NAD H2O NADH NH3 NADP NADPH H2O Xanthos Pi Pi Rib-1P H2O Inosine Pi PPi PRPP Pi Hyp Rib-1P PPi O2 H2O H2O2 NAD H2O Urate NADH D-Ino Pi D1P GTP Asp GDP Pi Asuca AMP H2O NH3 Fumarat Accumulation Adenosi H2O NH3 Pi Accumulation Adenine Rib-1P DA Pi D1P H2O NH3 PPi PRPP Accumulation ADP H2O Pi Accumulation ATP H2O Pi cAMP H2O PPi Accumulation ATP dAMP Accumulation ADP dADP H2O Pi Accumulation ATP Accumulation ADP Accumulation doATP 23CGMP PPi H2O IDP H2O Pi Ino3P H2O PPi Accumulation ATP Accumulation ADP H2O Pi PPi 5Ai4Ca PRPP Accumulation ATP Accumulation ADP Pi H2O Pi H2O H2O Mg2+ Ca2+ Mg2+ Ca2+ Mg2+ Mg2+ Mg2+ Mg2+ Zinc Mg2+ Mg2+ Mg2+ K+ Mg2+ Mg2+ Mg2+ Mg2+ FAD FAD Mg2+ Zinc Zinc Zinc Ca2+ Mg2+ Zinc Mg2+ Mg2+ Heme Zinc Mg2+ Ca2+ Mg2+ Mg2+ Ca2+ Disulfi Fe3+ Ca2+ Mg2+ Disulfi Fe3+ PW000055 Endoplasmic Reticulum Peroxisome Endoplasmic Reticulum Peroxisome Intracellular Space Extracellular Space Mitochondria