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Pyruvate carboxylase, mitochondrial L-lactate dehydrogenase A chain Pyruvate kinase PKLR Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Malate dehydrogenase, cytoplasmic Probable D-lactate dehydrogenase, mitochondrial Hydroxyacylglutathione hydrolase, mitochondrial Lactoylglutathione lyase Glyoxylate reductase/hydroxypyruvate reductase Aldose reductase Aldose reductase NADP-dependent malic enzyme Dihydrolipoyl dehydrogenase E3 Dihydrolipoyl transacetylase E2 Acetyl-CoA carboxylase 1 Acetyl-CoA acetyltransferase, mitochondrial Acyl-coenzyme A thioesterase 12 Acylphosphatase- 1 Aldehyde dehydrogenase, mitochondrial Acetyl-coenzyme A synthetase, cytoplasmic Acetyl-coenzyme A synthetase, cytoplasmic Pyruvate dehydrogenase E1 Accumulation Pyruvic acid Oxalacetic acid Phosphoenolpyruvic acid Pyruvaldehyde Acetyl-CoA Acetoacetyl-CoA ATP HCO3- ADP Pi L-Lactic acid NAD NADH H+ ATP ADP GTP GDP CO2 L-Malic acid NAD NADH H+ NAD CO2 NADH H+ D-Lactic acid H+ S-Lactoylglutathione H2O Glutathione Glutathione D-Lactaldehyde NAD NADH H+ Lactaldehyde NAD H+ NADH Propylene glycol NADP H+ NADPH NADP CO2 NADPH Dihydrolipoamide NAD Lipoamide NADH H+ S-Acetyldihydrolipoamide-E Coenzyme A ATP HCO3- Pi ADP Malonyl-CoA Coenzyme A CoA Acetic acid H2O Acetylphosphate H2O Pi Acetaldehyde NAD H2O NADH H+ ATP PPi Acetyl adenylate AMP PPi ATP CO2 Biotin Manganese Magnesium Potassium Manganese Zinc (II) ion Zinc (II) ion Manganese FAD Biotin Manganese Thiamine pyrophosphate Ferricytochrome c Ferrocytochrome c Nicotinate and Nicotinamide Metabolism Valine, Leucine, and Isoleucine Degradation Citric Acid Cycle Glycolysis Glycine and Serine Metabolism Propanoate Metabolism Ketone Body Metabolism Intracellular Space Mitochondria Mitochondrial matrix