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Acetyl-CoA acetyltransferase, mitochondrial 3-hydroxyacyl-CoA dehydrogenase type-2 Enoyl-CoA hydratase, mitochondrial Enoyl-[acyl- carrier- protein] reductase, mitochondrial 3-hydroxyacyl-CoA dehydrogenase type-2 Enoyl-CoA hydratase, mitochondrial Enoyl-[acyl- carrier- protein] reductase, mitochondrial Acetyl-CoA acyltransferase Acetyl-CoA acyltransferase 3-hydroxyacyl-CoA dehydrogenase type-2 Enoyl-CoA hydratase, mitochondrial Enoyl-[acyl- carrier- protein] reductase, mitochondrial Acetyl-CoA acyltransferase 3-hydroxyacyl-CoA dehydrogenase type-2 Enoyl-CoA hydratase, mitochondrial Enoyl-[acyl- carrier- protein] reductase, mitochondrial Acetyl-CoA acyltransferase Hydroxyacyl- coenzyme A dehydrogenase, mitochondrial Enoyl-CoA hydratase, mitochondrial Enoyl-[acyl- carrier- protein] reductase, mitochondrial Hydroxyacyl- coenzyme A dehydrogenase, mitochondrial Enoyl-CoA hydratase, mitochondrial Enoyl-[acyl- carrier- protein] reductase, mitochondrial Palmitoyl-protein thioesterase 1 Acetyl-CoA acetyltransferase, mitochondrial Palmitic acid Acetyl-CoA Butyryl-CoA 3-oxohexanoyl-CoA CoA 3- Hydroxyhexanoyl- CoA NAD NADH H+ (2E)-Hexenoyl-CoA H2O NADPH H+ Hexanoyl-CoA NADP 3- hydroxyoctanoyl- CoA NAD 3-oxooctanoyl-CoA H+ NADH (2E)-Octenoyl-CoA H2O NADPH H+ Octanoyl-CoA NADP Acetyl-CoA 3-oxodecanoyl-CoA CoA Acetyl-CoA CoA 3- Hydroxydecanoyl- CoA NAD H+ NADH (2E)-Decenoyl-CoA H2O NADPH H+ Decanoyl-CoA NADP Acetyl-CoA 3- oxododecanoyl- CoA CoA 3- Hydroxydodecanoyl- CoA NAD NADH H+ (2E)- Dodecenoyl-CoA H2O NADPH H+ Lauroyl-CoA NADP Acetyl-CoA 3- oxotetradecanoyl- CoA CoA 3- Hydroxytetradecanoyl- CoA NAD NADH H+ (2E)- Tetradecenoyl- CoA H2O NADPH H+ Tetradecanoyl-CoA NADP 3- Hydroxyhexadecanoyl- CoA NAD 3- oxohexadecanoyl- CoA NADH H+ (2E)- Hexadecenoyl- CoA H2O NADPH H+ hexadecanoyl-CoA NADP H2O CoA Acetyl-CoA CoA Fatty acid degradation Lysosome Mitochondria Cytosol