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3-methyl-2- oxobutanoate hydroxymethyltransferase 2 Probable 2-dehydropantoate 2-reductase Pantothenate synthetase pantothenate kinase Coenzyme A biosynthesis bifunctional protein CoaBC Coenzyme A biosynthesis bifunctional protein CoaBC Phosphopantetheine adenylyltransferase Dephospho-CoA kinase Probable 2-(5''- triphosphoribosyl)- 3'- dephosphocoenzyme- A synthase Dihydroxy-acid dehydratase Aspartate 1-decarboxylase α-Ketoisovaleric acid L-Aspartic acid 5,10-Methylene- THF H2O Tetrahydrofolic acid 2-dehydropantoate NADPH H+ NADP (R)-pantoate β-Alanine ATP AMP PPi H+ Pantothenic acid ATP ADP H+ D-4'- Phosphopantothenate Cytidine triphosphate L-Cysteine Cytidine monophosphate PPi H+ 4'- Phosphopantothenoylcysteine H+ CO2 4'- phosphopantetheine ATP H+ PPi Dephospho-CoA ATP H+ ADP Coenzyme A ATP H+ Adenine 2'-(5- Triphosphoribosyl)- 3'-dephospho- CoA 2,3- Dihydroxyisovaleric acid H2O H+ CO2 Valine Biosynthesis Aspartate Metabolism Ketol-acid reductoisomerase (NADP(+))
panB2 panE panC rmlD coaBC coaBC coaD coaE mdcB ilvD panD α-Ketoisovaleric acid L-Aspartic acid 5,10-Methylene- THF Water Tetrahydrofolic acid 2-dehydropantoate NADPH Hydrogen Ion NADP (R)-pantoate β-Alanine Adenosine triphosphate Adenosine monophosphate Pyrophosphate Hydrogen Ion Pantothenic acid Adenosine triphosphate Adenosine diphosphate Hydrogen Ion D-4'- Phosphopantothenate Cytidine triphosphate L-Cysteine Cytidine monophosphate Pyrophosphate Hydrogen Ion 4'- Phosphopantothenoylcysteine Hydrogen Ion Carbon dioxide 4'- phosphopantetheine Adenosine triphosphate Hydrogen Ion Pyrophosphate Dephospho-CoA Adenosine triphosphate Hydrogen Ion Adenosine diphosphate Coenzyme A Adenosine triphosphate Hydrogen Ion Adenine 2'-(5- Triphosphoribosyl)- 3'-dephospho- CoA 2,3- Dihydroxyisovaleric acid Water Hydrogen Ion Carbon dioxide Valine Biosynthesis Aspartate Metabolism ilvC
panB2 panE panC rmlD coaBC coaBC coaD coaE mdcB ilvD panD Ketoval Asp 5XM-THF H2O THFA 2Dhp NADPH H+ NADP Rpoate b-Ala ATP AMP PPi H+ VitB5 ATP ADP H+ 4PP CTP Cys CMP PPi H+ 4'PPCys H+ CO2 4'P ATP H+ PPi Dph-CoA ATP H+ ADP CoA ATP H+ Adenine 25T3DCA 2,3-Div H2O H+ CO2 PW000812 PW000787 ilvC
panB2 panE panC rmlD coaBC coaBC coaD coaE mdcB ilvD panD Ketoval Asp 5XM-THF H2O THFA 2Dhp NADPH H+ NADP Rpoate b-Ala ATP AMP Ppi H+ VitB5 ATP ADP H+ 4PP CTP Cys CMP Ppi H+ 4'PPCys H+ CO2 4'P ATP H+ Ppi Dph-CoA ATP H+ ADP CoA ATP H+ Adenine 25T3DCA 2,3-Div H2O H+ CO2 PW000812 PW000787 ilvC