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Amidophosphoribosyltransferase Phosphoribosylamine- -glycine ligase Phosphoribosylglycinamide formyltransferase Phosphoribosylformylglycinamidine synthase Phosphoribosylformylglycinamidine cyclo-ligase Phosphomethylpyrimidine synthase Thiamine- phosphate synthase Thiamine- monophosphate kinase Formate- dependent phosphoribosylglycinamide formyltransferase Phosphoribosyl pyrophosphate H2O L-Glutamine 5- Phosphoribosylamine L-Glutamic acid PPi Glycine ATP N1-(5- phospho-β-D- ribosyl)glycinamide Pi ADP H+ 10-formyl- tetrahydrofolate mono-L- glutamate H+ tetrahydropteroyl mono-L- glutamate 5'- Phosphoribosyl- N- formylglycinamide H2O L-Glutamine ATP 2- (Formamido)- N1-(5- phospho-D- ribosyl)acetamidine L-Glutamic acid Pi ADP H+ ATP 5- Aminoimidazole ribonucleotide Pi ADP H+ S- Adenosylmethionine H+ Carbon monoxide Formic acid L-Methionine 5'- Deoxyadenosine 4-amino-2- methyl-5- phosphomethylpyrimidine ATP ADP 4-amino-2- methyl-5- diphosphomethylpyrimidine 2-((2R,5Z)-2- Carboxy-4- methylthiazol- 5(2H)- ylidene)ethyl phosphate H+ CO2 PPi Thiamine monophosphate ATP ADP Thiamine pyrophosphate ATP Formic acid ADP Pi H+ Magnesium Magnesium Potassium Magnesium NADPH NADH NADPH S- Adenosylmethionine Magnesium Magnesium Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
purF purD purN purL purM thiC thiE thiL_2 purT Phosphoribosyl pyrophosphate Water L-Glutamine 5- Phosphoribosylamine L-Glutamic acid Pyrophosphate Glycine Adenosine triphosphate N1-(5- phospho-β-D- ribosyl)glycinamide Phosphate Adenosine diphosphate Hydrogen Ion 10-formyl- tetrahydrofolate mono-L- glutamate Hydrogen Ion tetrahydropteroyl mono-L- glutamate 5'- Phosphoribosyl- N- formylglycinamide Water L-Glutamine Adenosine triphosphate 2- (Formamido)- N1-(5- phospho-D- ribosyl)acetamidine L-Glutamic acid Phosphate Adenosine diphosphate Hydrogen Ion Adenosine triphosphate 5- Aminoimidazole ribonucleotide Phosphate Adenosine diphosphate Hydrogen Ion S- Adenosylmethionine Hydrogen Ion Carbon monoxide Formic acid L-Methionine 5'- Deoxyadenosine 4-amino-2- methyl-5- phosphomethylpyrimidine Adenosine triphosphate Adenosine diphosphate 4-amino-2- methyl-5- diphosphomethylpyrimidine 2-((2R,5Z)-2- Carboxy-4- methylthiazol- 5(2H)- ylidene)ethyl phosphate Hydrogen Ion Carbon dioxide Pyrophosphate Thiamine monophosphate Adenosine triphosphate Adenosine diphosphate Thiamine pyrophosphate Adenosine triphosphate Formic acid Adenosine diphosphate Phosphate Hydrogen Ion