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dGTP Amidophosphoribosyltransferase Phosphoribosylamine- -glycine ligase Formate- dependent phosphoribosylglycinamide formyltransferase Phosphoribosylformylglycinamidine synthase Phosphoribosylformylglycinamidine cyclo-ligase Phosphoribosylaminoimidazole- succinocarboxamide synthase Adenylosuccinate lyase Inosine-5'- monophosphate dehydrogenase Adenylosuccinate synthetase Adenylosuccinate lyase GMP synthase [glutamine- hydrolyzing] Guanylate kinase Nucleoside diphosphate kinase Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase subunit beta Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase Ribonucleoside- diphosphate reductase subunit beta Bifunctional purine biosynthesis protein PurH Cob(I)yrinic acid a,c-diamide adenosyltransferase Unknown Unknown N5- carboxyaminoimidazole ribonucleotide mutase N5- carboxyaminoimidazole ribonucleotide synthase Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase subunit beta Adenylate kinase ATP synthase subunit c ATP synthase subunit b ATP synthase subunit a ATP synthase epsilon chain ATP synthase subunit delta ATP synthase subunit alpha ATP synthase gamma chain ATP synthase subunit beta Nucleoside diphosphate kinase Ribonucleoside- diphosphate reductase subunit beta Nucleoside diphosphate kinase Bifunctional purine biosynthesis protein PurH Guanosine triphosphate Phosphoribosyl pyrophosphate H2O L-Glutamine 5- Phosphoribosylamine L-Glutamic acid PPi Glycine ATP N1-(5- phospho-β-D- ribosyl)glycinamide Pi ADP H+ ATP Formic acid 5'- Phosphoribosyl- N- formylglycinamide ADP Pi H+ H2O L-Glutamine ATP 2- (Formamido)- N1-(5- phospho-D- ribosyl)acetamidine L-Glutamic acid Pi ADP H+ ATP 5- Aminoimidazole ribonucleotide Pi ADP H+ 5-amino-1-(5- phospho-D- ribosyl)imidazole- 4-carboxylate L-Aspartic acid ATP SAICAR Pi ADP H+ AICAR Fumaric acid Inosinic acid NAD H2O NADH H+ Xanthylic acid L-Aspartic acid GTP GDP Pi H+ N(6)-(1,2- dicarboxyethyl)AMP Fumaric acid Adenosine monophosphate ATP L-Glutamine H2O AMP PPi L-Glutamic acid H+ Guanosine monophosphate ATP ADP Guanosine diphosphate ATP ADP H2O H2O dGDP Adenosine triphosphate H2O dATP Adenosine diphosphate H2O dADP 10- Formyltetrahydrofolate FAICAR tetrahydropteroyl mono-L- glutamate Cobalamin Triphosphate Adenosylcobalamin Itaconic acid CoA ADP Pi Itaconyl-CoA 5- Phosphoribosyl- 5- carboxyaminoimidazole HCO3- ATP ADP Pi H+ H2O ATP Pi H+ H2O H+ ATP ADP H2O ATP ADP H2O Magnesium Magnesium Potassium Magnesium Magnesium Magnesium Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium Zinc (II) ion 4Fe-4S Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium 4Fe-4S Magnesium Magnesium Magnesium a reduced flavodoxin an oxidized flavodoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein a reduced flavodoxin an oxidized flavodoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein reduced thioredoxin oxidized thioredoxin reduced thioredoxin oxidized thioredoxin Folate Biosynthesis PRPP Biosynthesis