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dGTP Amidophosphoribosyltransferase Phosphoribosylamine- -glycine ligase Formate- dependent phosphoribosylglycinamide formyltransferase Phosphoribosylformylglycinamidine synthase Phosphoribosylformylglycinamidine cyclo-ligase Phosphoribosylaminoimidazole- succinocarboxamide synthase Adenylosuccinate lyase Inosine-5'- monophosphate dehydrogenase Adenylosuccinate synthetase Adenylosuccinate lyase GMP synthase [glutamine- hydrolyzing] Guanylate kinase Nucleoside diphosphate kinase Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase subunit beta Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase Ribonucleoside- diphosphate reductase subunit beta Bifunctional purine biosynthesis protein PurH Cob(I)yrinic acid a,c-diamide adenosyltransferase Unknown Unknown N5- carboxyaminoimidazole ribonucleotide mutase N5- carboxyaminoimidazole ribonucleotide synthase Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase subunit beta Adenylate kinase ATP synthase subunit c ATP synthase subunit b ATP synthase subunit a ATP synthase epsilon chain ATP synthase subunit delta ATP synthase subunit alpha ATP synthase gamma chain ATP synthase subunit beta Nucleoside diphosphate kinase Ribonucleoside- diphosphate reductase subunit beta Nucleoside diphosphate kinase Bifunctional purine biosynthesis protein PurH Guanosine triphosphate Phosphoribosyl pyrophosphate H2O L-Glutamine 5- Phosphoribosylamine L-Glutamic acid PPi Glycine ATP N1-(5- phospho-β-D- ribosyl)glycinamide Pi ADP H+ ATP Formic acid 5'- Phosphoribosyl- N- formylglycinamide ADP Pi H+ H2O L-Glutamine ATP 2- (Formamido)- N1-(5- phospho-D- ribosyl)acetamidine L-Glutamic acid Pi ADP H+ ATP 5- Aminoimidazole ribonucleotide Pi ADP H+ 5-amino-1-(5- phospho-D- ribosyl)imidazole- 4-carboxylate L-Aspartic acid ATP SAICAR Pi ADP H+ AICAR Fumaric acid Inosinic acid NAD H2O NADH H+ Xanthylic acid L-Aspartic acid GTP GDP Pi H+ N(6)-(1,2- dicarboxyethyl)AMP Fumaric acid Adenosine monophosphate ATP L-Glutamine H2O AMP PPi L-Glutamic acid H+ Guanosine monophosphate ATP ADP Guanosine diphosphate ATP ADP H2O H2O dGDP Adenosine triphosphate H2O dATP Adenosine diphosphate H2O dADP 10- Formyltetrahydrofolate FAICAR tetrahydropteroyl mono-L- glutamate Cobalamin Triphosphate Adenosylcobalamin Itaconic acid CoA ADP Pi Itaconyl-CoA 5- Phosphoribosyl- 5- carboxyaminoimidazole HCO3- ATP ADP Pi H+ H2O ATP Pi H+ H2O H+ ATP ADP H2O ATP ADP H2O Magnesium Magnesium Potassium Magnesium Magnesium Magnesium Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium Zinc (II) ion 4Fe-4S Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium 4Fe-4S Magnesium Magnesium Magnesium a reduced flavodoxin an oxidized flavodoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein a reduced flavodoxin an oxidized flavodoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein reduced thioredoxin oxidized thioredoxin reduced thioredoxin oxidized thioredoxin Folate Biosynthesis PRPP Biosynthesis Ribonucleoside- diphosphate reductase Anaerobic ribonucleoside- triphosphate reductase Zinc (II) ion
dGTP purF purD purT purL purM purC purB guaB_1 purA purB guaA gmk ndk AO964_16150 nrdB_3 AO964_16150 nrdE2 nrdB_3 purH cobO Unknown Unknown purE purK AO964_16150 nrdB_2 adk atpE atpF atpB atpC atpH atpA atpG atpD ndk nrdB_2 ndk purH Guanosine triphosphate Phosphoribosyl pyrophosphate Water L-Glutamine 5- Phosphoribosylamine L-Glutamic acid Pyrophosphate Glycine Adenosine triphosphate N1-(5- phospho-β-D- ribosyl)glycinamide Phosphate Adenosine diphosphate Hydrogen Ion Adenosine triphosphate Formic acid 5'- Phosphoribosyl- N- formylglycinamide Adenosine diphosphate Phosphate Hydrogen Ion Water L-Glutamine Adenosine triphosphate 2- (Formamido)- N1-(5- phospho-D- ribosyl)acetamidine L-Glutamic acid Phosphate Adenosine diphosphate Hydrogen Ion Adenosine triphosphate 5- Aminoimidazole ribonucleotide Phosphate Adenosine diphosphate Hydrogen Ion 5-amino-1-(5- phospho-D- ribosyl)imidazole- 4-carboxylate L-Aspartic acid Adenosine triphosphate SAICAR Phosphate Adenosine diphosphate Hydrogen Ion AICAR Fumaric acid Inosinic acid NAD Water NADH Hydrogen Ion Xanthylic acid L-Aspartic acid Guanosine triphosphate Guanosine diphosphate Phosphate Hydrogen Ion N(6)-(1,2- dicarboxyethyl)AMP Fumaric acid Adenosine monophosphate Adenosine triphosphate L-Glutamine Water Adenosine monophosphate Pyrophosphate L-Glutamic acid Hydrogen Ion Guanosine monophosphate Adenosine triphosphate Adenosine diphosphate Guanosine diphosphate Adenosine triphosphate Adenosine diphosphate Water Water dGDP Adenosine triphosphate Water dATP Adenosine diphosphate Water dADP 10- Formyltetrahydrofolate FAICAR tetrahydropteroyl mono-L- glutamate Cobalamin Triphosphate Adenosylcobalamin Itaconic acid Coenzyme A Adenosine diphosphate Phosphate Itaconyl-CoA 5- Phosphoribosyl- 5- carboxyaminoimidazole Hydrogen carbonate Adenosine triphosphate Adenosine diphosphate Phosphate Hydrogen Ion Water Adenosine triphosphate Phosphate Hydrogen Ion Water Hydrogen Ion Adenosine triphosphate Adenosine diphosphate Water Adenosine triphosphate Adenosine diphosphate Water a reduced flavodoxin an oxidized flavodoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein a reduced flavodoxin an oxidized flavodoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein reduced thioredoxin oxidized thioredoxin reduced thioredoxin oxidized thioredoxin Folate Biosynthesis PRPP Biosynthesis nrdE2 AO964_16150
dGTP purF purD purT purL purM purC purB guaB_1 purA purB guaA gmk ndk AO964_16150 nrdB_3 AO964_16150 nrdE2 nrdB_3 purH cobO purE purK AO964_16150 nrdB_2 adk atpE atpF atpB atpC atpH atpA atpG atpD ndk nrdB_2 ndk purH GTP PRPP H2O Gln 5-PPRSA Glu PPi Gly ATP N15hg Pi ADP H+ ATP Formate 5PPNFG ADP Pi H+ H2O Gln ATP 2FN5PDR Glu Pi ADP H+ ATP 5-AnRbn Pi ADP H+ CR Asp ATP SAICAR Pi ADP H+ AICAR Fumarat Imp NAD H2O NADH H+ XntylcA Asp GTP GDP Pi H+ N6AMP Fumarat AMP ATP Gln H2O AMP PPi Glu H+ GSMP ATP ADP GDP ATP ADP H2O H2O dGDP ATP H2O dATP ADP H2O dADP 10-FTHF FAICAR TaMLGlu Ruvite PPP Adnscbn ItacnAc CoA ADP Pi Itc-CoA 5P5ca HCO3- ATP ADP Pi H+ H2O ATP Pi H+ H2O H+ ATP ADP H2O ATP ADP H2O Mg2+ Mg2+ K+ Mg2+ Mg2+ Mg2+ Mg2+ ATP dGTP Tm5TP K+ Mg2+ Zinc 4Fe-4S ATP dGTP Tm5TP K+ Mg2+ 4Fe-4S Mg2+ Mg2+ Mg2+ ARF AOF ARNGLP AONGLP ARF AOF ARNGLP AONGLP RT OT RT OT PW000908 PW000909 nrdE2 AO964_16150 Zinc
dGTP purF purD purT purL purM purC purB guaB_1 purA purB guaA gmk ndk AO964_16150 nrdB_3 AO964_16150 nrdE2 nrdB_3 purH cobO purE purK AO964_16150 nrdB_2 adk atpE atpF atpB atpC atpH atpA atpG atpD ndk nrdB_2 ndk purH GTP PRPP H2O Gln 5-PPRSA Glu Ppi Gly ATP N15hg Pi ADP H+ ATP Formate 5PPNFG ADP Pi H+ H2O Gln ATP 2FN5PDR Glu Pi ADP H+ ATP 5-AnRbn Pi ADP H+ CR Asp ATP SAICAR Pi ADP H+ AICAR Fumarat Imp NAD H2O NADH H+ XntylcA Asp GTP GDP Pi H+ N6AMP Fumarat AMP ATP Gln H2O AMP Ppi Glu H+ GSMP ATP ADP GDP ATP ADP H2O H2O dGDP ATP H2O dATP ADP H2O dADP 10-FTHF FAICAR TaMLGlu Ruvite PPP Adnscbn ItacnAc CoA ADP Pi Itc-CoA 5P5ca HCO3 ATP ADP Pi H+ H2O ATP Pi H+ H2O H+ ATP ADP H2O ATP ADP H2O ARF AOF ARNGLP AONGLP ARF AOF ARNGLP AONGLP RT OT RT OT PW000908 PW000909 nrdE2 AO964_16150