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NFKB1 Toll-like receptor 4 IRF3 STAT1 IRF3 IFNAR1 IFNAR2 IFNB1 NFKB1 NOS2 TNF IL6 IL1B ACOD1 CRH ACOD1 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate dehydrogenase cytochrome b560 subunit, mitochondrial Succinate dehydrogenase EGLN2 HIF1A SLC2A1 IL1B HK2 IL1B IL1B IL1B IL6 IFNAR1 IFNAR2 IFNB1 TNF NOS2 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 22 member 5 Solute carrier family 13 member 3 Solute carrier family 2, facilitated glucose transporter member 1 Monocarboxylate transporter 4 Histone H4 Importin-4 IL1B Interleukin enhancer- binding factor 3 Exportin-5 Low affinity cationic amino acid transporter 2 Solute carrier family 22 member 8 Solute carrier family 22 member 2 Solute carrier family 22 member 2 Solute carrier family 22 member 8 Interleukin Transport IL6 IL1B TNF IFNAR1 IFNAR2 IFNB1 IL1B IL1B IL6 IL6 TNF TNF NOS2 PKM PKM PKM Tetrahydrobiopterin MYD88 TICAM2 Flavin Mononucleotide Flavin Mononucleotide Tetrahydrobiopterin TICAM1 PKM Lipopolysaccharide Adrenocorticotropic hormone Adrenocorticotropic hormone Cortisol Epinephrine D-Glucose L-Lactic acid NO Citric acid L-Acetylcarnitine D-Glucose D-Glucose L-Acetylcarnitine L-Acetylcarnitine NO NO Succinic acid Succinic acid L-Lactic acid L-Arginine L-Arginine Cortisol Epinephrine Epinephrine Cortisol H+ NADPH O2 L-Arginine Citrulline NADP H2O Q FAD Fumaric acid QH2 FADH2 H+ NADPH O2 Citrulline NADP H2O NO L-Threonine L-Lysine L-Tryptophan L-Leucine L-Isoleucine L-Valine L-Arginine Glycine L-Serine Heme FAD 2Fe-2S Heme FAD Heme FAD Flavin Mononucleotide Tetrahydrobiopterin Succinic acid Succinic acid Succinic acid HIF1A HIF1A Aerobic Glycolysis (Warburg Effect) Aerobic Glycolysis (Warburg Effect) Aerobic Glycolysis (Warburg Effect) Anti- inflammatory pathway Bacteria Cleared Tricarboxylic acid cycle FAD Fe2+ Ascorbic acid Inflammasome Nucleus Cell Division Hypothalamus Pituitary Gland Adrenal Cortex Liver Blood Vessel Macrophage Blood Vessel Mitochondria Dilation
Melanosome Melanosome Nucleus NFKB1 TLR4 IRF3 STAT1 IRF3 IFNAR1 IFNAR2 IFNB1 NFKB1 NOS2 TNF IL6 IL1B ACOD1 CRH ACOD1 SDHA SDHB SDHC SDHD EGLN2 HIF1A SLC2A1 IL1B HK2 IL1B IL1B IL1B IL6 IFNAR1 IFNAR2 IFNB1 TNF NOS2 SLC2A2 SLC22A5 SLC13A3 SLC2A1 SLC16A3 HIST1H4A IPO4 IL1B ILF3 XPO5 SLC7A2 SLC22A8 SLC22A2 SLC22A2 SLC22A8 Unknown IL6 IL1B TNF IFNAR1 IFNAR2 IFNB1 IL1B IL1B IL6 IL6 TNF TNF NOS2 PKM PKM PKM MYD88 TICAM2 TICAM1 PKM Lipopolysaccharide Adrenocorticotropic hormone Adrenocorticotropic hormone Cortisol Epinephrine D-Glucose L-Lactic acid Nitric oxide Citric acid L-Acetylcarnitine D-Glucose D-Glucose L-Acetylcarnitine L-Acetylcarnitine Nitric oxide Nitric oxide Succinic acid Succinic acid L-Lactic acid L-Arginine L-Arginine Cortisol Epinephrine Epinephrine Cortisol Hydrogen Ion NADPH Oxygen L-Arginine Citrulline NADP Water Coenzyme Q10 FAD Fumaric acid QH2 FADH Hydrogen Ion NADPH Oxygen Citrulline NADP Water Nitric oxide L-Threonine L-Lysine L-Tryptophan L-Leucine L-Isoleucine L-Valine L-Arginine Glycine L-Serine Succinic acid Succinic acid Succinic acid HIF1A HIF1A Aerobic Glycolysis (Warburg Effect) Aerobic Glycolysis (Warburg Effect) Aerobic Glycolysis (Warburg Effect) Anti-inflammatory pathway Bacteria Cleared Tricarboxylic acid cycle