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Alkaline
phosphatase,
tissue-
nonspecific
isozyme
Pyridoxine-
5'-phosphate
oxidase
Aldehyde
oxidase
Pyridoxine-
5'-phosphate
oxidase
Pyridoxal
kinase
Pyridoxal
kinase
Pyridoxal
kinase
Pyridoxine-
5'-phosphate
oxidase
Pyridoxine-
5'-phosphate
oxidase
Alkaline
phosphatase,
tissue-
nonspecific
isozyme
Pyridoxal
phosphate
phosphatase
Pyridoxal
phosphate
phosphatase
Pyridoxal
phosphate
phosphatase
Pyridoxal 5'-phosphate
Pyridoxal
Pyridoxal
Pyridoxamine
Pyridoxamine
Pyridoxal 5'-phosphate
H
2
O
P
i
H
2
O
O
2
NH
3
H
2
O
2
O
2
H
2
O
4-Pyridoxic acid
H
2
O
2
2-Methyl-3-hydroxy-5-
formylpyridine-4-carboxylate
3-Hydroxy-2-methylpyridine-
4,5-dicarboxylate
Glycolaldehyde
Pyridoxine
O
2
H
2
O
2
P
i
Pyridoxine 5'-phosphate
H
2
O
H
2
O
P
i
P
i
Pyridoxamine 5'-phosphate
H
2
O
H
2
O
O
2
NH
3
H
2
O
2
O
2
H
2
O
2
P
i
Pyridoxamine 5'-phosphate
H
2
O
FAD
Molybdopterin
Zinc
Zinc
Zinc
Magnesium
Magnesium
Magnesium
Valine,
Leucine, and
Isoleucine
Degradation
Gluconeogenesis
Tyrosine
Metabolism
Porphyrin
Metabolism
Sphingolipid
Metabolism
Glycine and
Serine
Metabolism
Phenylalanine
and Tyrosine
Metabolism
Flavin
Mononucleotide
Flavin
Mononucleotide
Flavin
Mononucleotide
Flavin
Mononucleotide
Extracellular Space
Cytosol
Poor feeding, irritability,
hypotonia (state of low
muscle tone), failure to
thrive and seizures
ALPL
PNPO
AOX1
PNPO
PDXK
PDXK
PDXK
PNPO
PNPO
ALPL
PDXP
PDXP
PDXP
Pyridoxal
5'-phosphate
Pyridoxal
Pyridoxal
Pyridoxamine
Pyridoxamine
Pyridoxal
5'-phosphate
Water
Phosphoric acid
Water
Oxygen
Ammonia
Hydrogen
peroxide
Oxygen
Water
4-Pyridoxic
acid
Hydrogen
peroxide
2-Methyl-3-
hydroxy-5-
formylpyridine-
4-carboxylate
3-Hydroxy-2-
methylpyridine-
4,5-
dicarboxylate
Glycolaldehyde
Pyridoxine
Oxygen
Hydrogen
peroxide
Phosphoric acid
Pyridoxine
5'-phosphate
Water
Water
Phosphoric acid
Phosphoric acid
Pyridoxamine
5'-phosphate
Water
Water
Oxygen
Ammonia
Hydrogen
peroxide
Oxygen
Hydrogen
peroxide
Phosphoric acid
Pyridoxamine
5'-phosphate
Water
Valine,
Leucine, and
Isoleucine
Degradation
Gluconeogenesis
Tyrosine
Metabolism
Porphyrin
Metabolism
Sphingolipid
Metabolism
Glycine and
Serine
Metabolism
Phenylalanine
and Tyrosine
Metabolism