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Solute carrier
family 2,
facilitated
glucose
transporter
member 2
Solute carrier
family 2,
facilitated
glucose
transporter
member 2
Mitochondrial
pyruvate
carrier 1
Mitochondrial
pyruvate
carrier 1
Glucose-6-
phosphate
translocase
Monocarboxylate
transporter 1
Glucose-6-
phosphatase
Glucose-6-
phosphatase
Phosphoglucomutase-
1
Glucose-6-
phosphate
isomerase
Hexokinase-2
Aldose
1-epimerase
Hexokinase-2
Glucose-6-
phosphate
isomerase
Fructose-1,6-
bisphosphatase
1
Fructose-
bisphosphate
aldolase A
Triosephosphate
isomerase
Glyceraldehyde-
3-phosphate
dehydrogenase
Pantothenate
kinase 1
Phosphoglycerate
mutase 2
Alpha-enolase
Bisphosphoglycerate
mutase
Bisphosphoglycerate
mutase
Phosphoglycerate
mutase 1
Phosphoenolpyruvate
carboxykinase,
cytosolic [GTP]
Malate
dehydrogenase,
mitochondrial
Malate
dehydrogenase,
mitochondrial
Pyruvate
carboxylase,
mitochondrial
Phosphoenolpyruvate
carboxykinase,
cytosolic [GTP]
L-lactate
dehydrogenase
A-like 6A
Pyruvate
carboxylase,
mitochondrial
D-Glucose
Glucose 1-phosphate
D-Glyceraldehyde 3-phosphate
Fructose 6-phosphate
Phosphoenolpyruvic acid
Pyruvic acid
L-Lactic acid
3-Phosphoglyceric acid
Pyruvic acid
D-Glucose
D-Glucose
P
i
P
i
Oxoglutaric acid
Oxoglutaric acid
Malic acid
Malic acid
Phosphoenolpyruvic acid
Pyruvic acid
Pyruvic acid
Glucose 6-phosphate
Glucose 6-phosphate
L-Lactic acid
H
2
O
H
2
O
P
i
α-D-Glucose
ATP
ADP
β-D-Glucose
ATP
ADP
β-D-Glucose 6-phosphate
Fructose 1,6-bisphosphate
H
2
O
P
i
Dihydroxyacetone phosphate
NAD
P
i
Glyceric acid 1,3-biphosphate
NADH
ATP
ADP
2-Phospho-D-glyceric acid
H
2
O
2,3-Diphosphoglyceric acid
H
2
O
P
i
H
2
O
P
i
GTP
Oxalacetic acid
GDP
CO
2
NAD
NADH
H
+
NAD
Oxalacetic acid
NADH
H
+
ATP
HCO
3
-
ADP
P
i
GTP
Oxalacetic acid
GDP
CO
2
NAD
NADH
H
+
ATP
HCO
3
-
ADP
P
i
Biotin
Manganese
Biotin
Manganese
Galactose
Metabolism
Nucleotide
Sugars
Metabolism
Starch and
Sucrose
Metabolism
Pentose
Phosphate
Pathway
Fructose and
Mannose
Degradation
Galactose
Metabolism
Thiamine
Metabolism
Phenylalanine
and Tyrosine
Metabolism
Pyruvate
Metabolism
Pantothenate
and CoA
Biosynthesis
Aspartate
Metabolism
Tyrosine
Metabolism
Propanoate
Metabolism
Glycerolipid
Metabolism
Alanine
Metabolism
Pyruvate
Metabolism
Mitochondrial
2-
oxoglutarate/malate
carrier protein
Magnesium
Magnesium
Manganese
Magnesium
Manganese
Capillary Bed
Mitochondria
Endoplasmic Reticulum
Intracellular Space
Extracellular Space
Cytosol
Symptoms of the disorder
include hepatomegaly,
failure to thrive and liver
failure