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Penicillin- binding protein 1A Penicillin binding protein 2a Penicillin- binding protein 1A Penicillin binding protein 2a Cefmetazole Cefmetazole NAM-NAG peptide NAM-NAG peptide NAM-NAG peptide NAM-NAG peptide Autolytic enzyme Autolytic enzyme Autolytic enzyme Autolytic enzyme Cross-linking and peptidoglycan synthesis Peptidoglycan Cross-linking and peptidoglycan synthesis Peptidoglycan Cefmetazole inhibits the enzyme penicillin binding proteins which are responsible for glycosyltransferase and transpeptidase reactions that lead to cross-linking of D-alanine and D-aspartic acid in bacterial cell walls. Cytosol Cytosol Gram-positive bacteria Gram-positive bacteria Periplasmic space Periplasmic space Autolytic enzymes are upregulated and activated leading to cell wall lysis Periplasmic space Peptidoglycan Gram-negative bacteria Cytosol Cross-linking and peptidoglycan synthesis Gram-negative bacteria Cytosol Peptidoglycan Cross-linking and peptidoglycan synthesis Periplasmic space Cefmetazole inhibits the enzyme penicillin binding proteins which are responsible for glycosyltransferase and transpeptidase reactions that lead to cross-linking of D-alanine and D-aspartic acid in bacterial cell walls.
Peroxisome Peroxisome Peroxisome Peroxisome mrcA mecA mrcA mecA Cefmetazole Cefmetazole NAM-NAG peptide NAM-NAG peptide NAM-NAG peptide NAM-NAG peptide Autolytic enzyme Autolytic enzyme Autolytic enzyme Autolytic enzyme
mrcA mecA mrcA mecA Cefmeta Cefmeta NA-NA p NA-NA p NA-NA p NA-NA p Aut enz Aut enz Aut enz Aut enz Cross-linking and peptidoglycan synthesis Peptidoglycan Cross-linking and peptidoglycan synthesis Peptidoglycan Cefmetazole inhibits the enzyme penicillin binding proteins which are responsible for glycosyltransferase and transpeptidase reactions that lead to cross-linking of D-alanine and D-aspartic acid in bacterial cell walls. Cytosol Cytosol Gram-positive bacteria Gram-positive bacteria Periplasmic space Periplasmic space Autolytic enzymes are upregulated and activated leading to cell wall lysis Periplasmic space Peptidoglycan Gram-negative bacteria Cytosol Cross-linking and peptidoglycan synthesis Gram-negative bacteria Cytosol Peptidoglycan Cross-linking and peptidoglycan synthesis Periplasmic space Cefmetazole inhibits the enzyme penicillin binding proteins which are responsible for glycosyltransferase and transpeptidase reactions that lead to cross-linking of D-alanine and D-aspartic acid in bacterial cell walls.
Peroxisome Peroxisome Peroxisome Peroxisome mrcA mecA mrcA mecA Cefmeta Cefmeta NA-NA p NA-NA p NA-NA p NA-NA p Aut enz Aut enz Aut enz Aut enz