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Pathway Description
Moricizine Action Pathway
Homo sapiens
Category:
Metabolite Pathway
Sub-Category:
Drug Action
Created: 2023-09-04
Last Updated: 2023-11-27
Moricizine is an antiarrhythmic used to treat arrhythmias (irregular heartbeats) and to maintain normal heart rate. it acts on heart muscles by inhibiting inward sodium channels. This results in a slowed atrioventricular nodal and His-Purkinje conduction, which decreases excitability conduction velocity, and automaticity. It decreases the maximum rate of phase 0 depolarization, but it does not affect action potential amplitude, sinoatrial (SA) nodal or intra-atrial conduction, or maximum diastolic potential. It minimally effects sinus cycle length and sinus node recovery time.
References
Moricizine Pathway References
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