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Glycerol-3- phosphate dehydrogenase [NAD(+)], cytoplasmic Glycerol-3- phosphate acyltransferase 1-Acyl-sn- glycerol-3- phosphate acyltransferase Phosphatidate phosphatase Diacylglycerol O-acyltransferase Dihydroxyacetone phosphate NADH H+ NAD Glycerol 3-phosphate γ-Linolenoyl-CoA CoA LysoPA(18:3(6Z,9Z,12Z)/0:0) LysoPA(18:3(6Z,9Z,12Z)/0:0) Docosahexaenoyl- CoA CoA PA(18:3(6Z,9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) H2O DG(18:3(6Z,9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) Pi Osbondoyl-CoA TG(18:3(6Z,9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z)) CoA Glycolysis Mitochondria Outer Membrane Endoplasmic Reticulum Membrane Cytosol
Mitochondria Endoplasmic Reticulum Gpd1l Gpat2 Agpat1 Lpin2 Unknown Dihydroxyacetone phosphate NADH Hydrogen Ion NAD Glycerol 3-phosphate γ-Linolenoyl-CoA Coenzyme A LysoPA(18:3(6Z,9Z,12Z)/0:0) LysoPA(18:3(6Z,9Z,12Z)/0:0) Docosahexaenoyl- CoA Coenzyme A PA(18:3(6Z,9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) Water DG(18:3(6Z,9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) Phosphate Osbondoyl-CoA TG(18:3(6Z,9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z)) Coenzyme A Glycolysis