PathBank

Pathway Description

Pyruvate Decarboxylation to Acetyl-CoA

Providencia rettgeri DSM 1131

Category:

Metabolite Pathway

Sub-Category:

Metabolic

Created: 2024-10-05

Last Updated: 2024-10-05

The multi-enzyme complex catalyze three reactions that constitute a cycle, which is an essential source of acetyl-CoA. Pyruvate dehydrogenase E1 and dihydrolipoyllysine-residue acetyltransferase catalyzes pyruvic acid to acetyl-CoA and CO2. Acetyl-CoA is required for the TCA cycle. Lipoamide dehydrogenase reduces NAD+ to NADH.

References

Pyruvate Decarboxylation to Acetyl-CoA References

This pathway was propagated using PathWhiz - Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.

Propagated from SMP0002095

Enter relative concentration values (without units). Elements will be highlighted in a color gradient where red = lowest concentration and green = highest concentration. For the best results, view the pathway in Black and White.

Visualize Compound Data

		Acetyl-CoA
		Carbon dioxide
		Coenzyme A
		Hydrogen Ion
		NAD
		NADH
		Pyruvic acid

Visualize Protein Data

		Dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (Succinyl-transferring) complex
		Pyridine nucleotide-disulfide oxidoreductase
		Transketolase

Downloads

SVG Image

Simple SVG Image

Greyscale SVG Image

BioPAX

SBGN

SBML

PWML

PNG Image

All files (.zip)

Settings

Loading Pathway...

Pyruvate Decarboxylation to Acetyl-CoA

Pyruvate Decarboxylation to Acetyl-CoA References