PathBank

Pathway Description

Pyruvate Decarboxylation to Acetyl-CoA

Roseburia inulinivorans DSM 16841

Category:

Metabolite Pathway

Sub-Category:

Metabolic

Created: 2024-10-05

Last Updated: 2024-10-05

The multi-enzyme complex catalyze three reactions that constitute a cycle, which is an essential source of acetyl-CoA. Pyruvate dehydrogenase E1 and dihydrolipoyllysine-residue acetyltransferase catalyzes pyruvic acid to acetyl-CoA and CO2. Acetyl-CoA is required for the TCA cycle. Lipoamide dehydrogenase reduces NAD+ to NADH.

References

Pyruvate Decarboxylation to Acetyl-CoA References

This pathway was propagated using PathWhiz - Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.

Propagated from SMP0002095

Enter relative concentration values (without units). Elements will be highlighted in a color gradient where red = lowest concentration and green = highest concentration. For the best results, view the pathway in Black and White.

Visualize Compound Data

		Acetyl-CoA
		Carbon dioxide
		Coenzyme A
		Hydrogen Ion
		NAD
		NADH
		Pyruvic acid

Visualize Protein Data

		Biotin-requiring enzyme
		Pyridine nucleotide-disulfide oxidoreductase
		Transketolase, thiamine diphosphate binding domain protein

Downloads

SVG Image

Simple SVG Image

Greyscale SVG Image

BioPAX

SBGN

SBML

PWML

PNG Image

All files (.zip)

Settings

Loading Pathway...

Pyruvate Decarboxylation to Acetyl-CoA

Pyruvate Decarboxylation to Acetyl-CoA References