PathBank

Pathway Description

Hydrogen Sulfide Biosynthesis I

Brachyspira pilosicoli B2904

Category:

Metabolite Pathway

Sub-Category:

Metabolic

Created: 2024-11-21

Last Updated: 2025-06-01

Many bacteria can produce hydrogen sulfide, which can be used as defense system against antibiotics and oxidative stress. This pathway is one of the hydrogen sulfide biosynthesis pathways (totally two). L-Cysteine is transported by L-cysteine ABC transporter and convert to 3-mercaptopyruvic acid by facilitation of aspartate aminotransferase. 3-Mercaptopyruvic acid is later catalyzed to form pyruvic acid and hydrogen sulfide by 3-mercaptopyruvate sulfurtransferase.

References

Hydrogen Sulfide Biosynthesis I References

This pathway was propagated using PathWhiz - Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.

Propagated from SMP0002078

Enter relative concentration values (without units). Elements will be highlighted in a color gradient where red = lowest concentration and green = highest concentration. For the best results, view the pathway in Black and White.

Visualize Compound Data

		3-Mercaptopyruvic acid
		Adenosine diphosphate
		Adenosine triphosphate
		Hydrogen Ion
		Hydrogen sulfide
		L-Cysteine
		L-Glutamic acid
		Oxoglutaric acid
		Phosphate
		Pyruvic acid
		Water

Visualize Protein Data

		Amino acid transport ATP-binding protein
		His/Glu/Gln/Arg/opine family amino acid ABC transporter permease
		Polar amino acid uptake ABC transporter amino acid-binding protein
		Rhodanese domain protein
		Unknown