PathBank

Pathway Description

Oleic Acid Oxidation

Escherichia coli (strain K12 / MC4100 / BW2952)

Category:

Metabolite Pathway

Sub-Category:

Metabolic

Created: 2025-01-27

Last Updated: 2025-06-12

The process of oleic acid B-oxidation starts with a 2-trans,5-cis-tetradecadienoyl-CoA that can be either be processed by an enoyl-CoA hydratase by interacting with a water molecules resulting in a 3-hydroxy-5-cis-tetradecenoyl-CoA, which can be oxidized in the fatty acid beta-oxidation. On the other hand 2-trans,5-cis-tetradecadienoyl-CoA can become a 3-trans,5-cis-tetradecadienoyl-CoA through a isomerase. This results interact with a water molecule through a acyl-CoA thioesterase resulting in a hydrogen ion, a coenzyme A and a 3,5-tetradecadienoate

References

Oleic Acid Oxidation References

This pathway was propagated using PathWhiz - Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.

Propagated from SMP0002039

Highlighted elements will appear in red.

Highlight Compounds

	2-trans,5-cis-tetradecadienoyl-CoA
	3,5-tetradecadienoate
	3,5-Tetradecadienoyl-CoA
	3-hydroxy-5-cis-tetradecenoyl-CoA
	Coenzyme A
	Hydrogen Ion
	Water

Highlight Proteins

	ATPase RavA
	Fatty acid oxidation complex subunit alpha

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