PathBank

Pathway Description

Curcumin Degradation

Subdoligranulum variabile DSM 15176

Category:

Metabolite Pathway

Sub-Category:

Metabolic

Created: 2025-01-30

Last Updated: 2025-06-13

Curcumin is metabolized by being reduced through a NADPH dependent curcumin reductase resulting in a dihydrocurcumin. This compound is then reduced again through a NADPH-dependent dihydrocurcumin reductase resulting in a tetrahydrocurcumin. It is not know yet how this compound enters E.coli

References

Curcumin Degradation References

This pathway was propagated using PathWhiz - Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.

Propagated from SMP0001910

Highlighted elements will appear in red.

Highlight Compounds

	Curcumin
	Dihydrocurcumin
	Hydrogen Ion
	NADP
	NADPH
	Tetrahydrocurcumin

Highlight Proteins

Radical SAM domain protein

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