PathBank

Pathway Description

Guanine and Guanosine Salvage

Oxalobacter formigenes HOxBLS

Category:

Metabolite Pathway

Sub-Category:

Metabolic

Created: 2025-02-09

Last Updated: 2025-06-17

Guanosine can be converted into guanine through a phosphate driven guanosine phosphorylase resulting in the release of an alpha-D-ribose 1 phosphate and a guanine. This compound in turn reacts with a PRPP through a guanine phosphoribosyltransferase resulting in the release of a pyrophosphate and a GMP. Guanosine can also react with and ATP driven guanosine kinase resulting in the release of an ADP, s hydrogen ion and a GMP

References

Guanine and Guanosine Salvage References

This pathway was propagated using PathWhiz - Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.

Propagated from SMP0002086

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Visualize Compound Data

		Adenosine diphosphate
		Adenosine triphosphate
		Guanine
		Guanosine
		Guanosine monophosphate
		Hydrogen Ion
		Phosphate
		Phosphoribosyl pyrophosphate
		Pyrophosphate
		Ribose 1-phosphate