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Pathway Description
Hydrogen Sulfide Biosynthesis I
Pseudomonas aeruginosa
Category:
Metabolite Pathway
Sub-Category:
Metabolic
Created: 2025-06-18
Last Updated: 2025-06-18
Many bacteria can produce hydrogen sulfide, which can be used as defense system against antibiotics and oxidative stress. This pathway is one of the hydrogen sulfide biosynthesis pathways (totally two). L-Cysteine is transported by L-cysteine ABC transporter and convert to 3-mercaptopyruvic acid by facilitation of aspartate aminotransferase. 3-Mercaptopyruvic acid is later catalyzed to form pyruvic acid and hydrogen sulfide by 3-mercaptopyruvate sulfurtransferase.
References
Hydrogen Sulfide Biosynthesis I References
Yan J, Deforet M, Boyle KE, Rahman R, Liang R, Okegbe C, Dietrich LEP, Qiu W, Xavier JB: Bow-tie signaling in c-di-GMP: Machine learning in a simple biochemical network. PLoS Comput Biol. 2017 Aug 2;13(8):e1005677. doi: 10.1371/journal.pcbi.1005677. eCollection 2017 Aug.
Pubmed: 28767643
This pathway was propagated using PathWhiz -
Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.
Propagated from SMP0002078
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