Sulfacytine is a short-acting antibiotic from the sulfonamide drug class. This drug class consists of synthetic bacteriostatic antibiotics with a broad spectrum against most gram-positive and many gram-negative organisms. Sulfacytine is indicated in the treatment of acute urinary tract infections. Sulfacytine inhibits the multiplication of bacteria by acting as a competitive inhibitor of dihydropteroate synthase in the folic acid metabolism cycle. This enzyme does the condensation of the pteridine with the para-aminobenzoic acid (PABA). The inhibition causes the bacteria to stop growing. This drug is administered as an oral tablet but was discontinued in 2006 (FDA).

Sulfacytine Pathway References