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Pathway Description
Isoleucine Degradation
Escherichia coli
Category:
Metabolite Pathway
Sub-Category:
Metabolic
Created: 2025-06-21
Last Updated: 2025-06-21
Isoleucine degradation is a vital metabolic process that breaks down the essential amino acid isoleucine into intermediates that feed into the tricarboxylic acid (TCA) cycle, facilitating energy production and various biosynthetic pathways. This pathway involves multiple enzymatic steps that convert isoleucine into acetyl-CoA and propionyl-CoA, key molecules for cellular metabolism. These reactions help in generating energy and providing building blocks for the synthesis of other important compounds.
References
Isoleucine Degradation References
This pathway was propagated using PathWhiz -
Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.
Propagated from SMP0271538
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