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Showing 346061 - 346070 of 605359 pathways

PathBank ID	Pathway Name and Description	Pathway Class	Chemical Compounds	Proteins
SMP0174312 View Pathway	Betrixaban Predicted Metabolism Pathway new Homo sapiens Metabolites of Betrixaban are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolite Metabolic	Betrixaban Betrixaban PIS1M1 Heme	Cytochrome P450 3A4
SMP0174310 View Pathway	Benorilate Predicted Metabolism Pathway new Homo sapiens Metabolites of Benorilate are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolite Metabolic	Benorilate Benorilate PIS1M1 Heme	Cytochrome P450 3A4
SMP0174286 View Pathway	De Novo Triacylglycerol Biosynthesis TG(18:4(6Z,9Z,12Z,15Z)/16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) Rattus norvegicus A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are also present in the blood to enable the bidirectional transference of adipose fat and blood glucose from the liver, and are a major component of human skin oils. (Wikipedia) De novo biosynthesis of triglycerides is also known as the phosphatidic acid pathway, and it is mainly associated with the liver and adipose tissue. All membrane-localized enzymes are coloured dark green in the image. First, dihydroxyacetone phosphate (or glycerone phosphate) from glycolysis is used by the cytosolic enzyme glycerol-3-phosphate dehydrogenase [NAD(+)] to synthesize sn-glycerol 3-phosphate. Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). The next three steps are localized to the endoplasmic reticulum membrane. The enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the glycerol backbone. Next, magnesium-dependent phosphatidate phosphatase catalyzes the conversion of phosphatidic acid into diacylglycerol. Last, the enzyme diacylglycerol O-acyltransferase synthesizes triacylglycerol from diacylglycerol and a fatty acyl-CoA. BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolite Metabolic
SMP0174354 View Pathway	Dihydroergocornine Predicted Metabolism Pathway new Homo sapiens Metabolites of Dihydroergocornine are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolite Metabolic	Dihydroergocornine Dihydroergocornine PIS1M1 Heme	Cytochrome P450 3A4
SMP0174359 View Pathway	Dorzolamide Predicted Metabolism Pathway new Homo sapiens Metabolites of Dorzolamide are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolite Metabolic	Dorzolamide Dorzolamide PIS1M1 Heme	Cytochrome P450 3A4
SMP0174340 View Pathway	Clofibrate Predicted Metabolism Pathway new Homo sapiens Metabolites of Clofibrate are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolite Metabolic	Clofibrate Clofibrate PIS1M1 Heme	Cytochrome P450 3A4
SMP0174335 View Pathway	Clenbuterol Predicted Metabolism Pathway new Homo sapiens Metabolites of Clenbuterol are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolite Metabolic	Clenbuterol Clenbuterol PIS1M1 Heme	Cytochrome P450 3A4
SMP0174347 View Pathway	Dasatinib Predicted Metabolism Pathway new Homo sapiens Metabolites of Dasatinib are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolite Metabolic	Dasatinib Dasatinib PIS1M1 Heme	Cytochrome P450 3A4
SMP0174329 View Pathway	Ceftobiprole medocaril Predicted Metabolism Pathway new Homo sapiens Metabolites of Ceftobiprole medocaril are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolite Metabolic	Ceftobiprole medocaril Ceftobiprole medocaril PIS1M1 Heme	Cytochrome P450 3A4
SMP0174361 View Pathway	Elvitegravir Predicted Metabolism Pathway new Homo sapiens Metabolites of Elvitegravir are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolite Metabolic	Elvitegravir Elvitegravir PIS1M1 Heme	Cytochrome P450 3A4

Showing 346061 - 346070 of 364398 pathways