Browsing Pathways

Wild-Type E.coli K-12 can not directly use D-arabinose as a sole source of carbon and energy; hence, E.coli uses the enzymes of the fucose degradation pathway to degrade D-arabinose for further utilization. D-arabinose can be metabolized to form dihydroxy-acetone phosphate for entering the central metabolism. Glycolaldehyde can be further catalyzed to form glycolic acid by lactaldehyde dehydrogenase.

Wild-Type E.coli K-12 can not directly use D-arabinose as a sole source of carbon and energy; hence, E.coli uses the enzymes of the fucose degradation pathway to degrade D-arabinose for further utilization. D-arabinose can be metabolized to form dihydroxy-acetone phosphate for entering the central metabolism. Glycolaldehyde can be further catalyzed to form glycolic acid by lactaldehyde dehydrogenase.

Wild-Type E.coli K-12 can not directly use D-arabinose as a sole source of carbon and energy; hence, E.coli uses the enzymes of the fucose degradation pathway to degrade D-arabinose for further utilization. D-arabinose can be metabolized to form dihydroxy-acetone phosphate for entering the central metabolism. Glycolaldehyde can be further catalyzed to form glycolic acid by lactaldehyde dehydrogenase.

Wild-Type E.coli K-12 can not directly use D-arabinose as a sole source of carbon and energy; hence, E.coli uses the enzymes of the fucose degradation pathway to degrade D-arabinose for further utilization. D-arabinose can be metabolized to form dihydroxy-acetone phosphate for entering the central metabolism. Glycolaldehyde can be further catalyzed to form glycolic acid by lactaldehyde dehydrogenase.

Wild-Type E.coli K-12 can not directly use D-arabinose as a sole source of carbon and energy; hence, E.coli uses the enzymes of the fucose degradation pathway to degrade D-arabinose for further utilization. D-arabinose can be metabolized to form dihydroxy-acetone phosphate for entering the central metabolism. Glycolaldehyde can be further catalyzed to form glycolic acid by lactaldehyde dehydrogenase.

Wild-Type E.coli K-12 can not directly use D-arabinose as a sole source of carbon and energy; hence, E.coli uses the enzymes of the fucose degradation pathway to degrade D-arabinose for further utilization. D-arabinose can be metabolized to form dihydroxy-acetone phosphate for entering the central metabolism. Glycolaldehyde can be further catalyzed to form glycolic acid by lactaldehyde dehydrogenase.

Wild-Type E.coli K-12 can not directly use D-arabinose as a sole source of carbon and energy; hence, E.coli uses the enzymes of the fucose degradation pathway to degrade D-arabinose for further utilization. D-arabinose can be metabolized to form dihydroxy-acetone phosphate for entering the central metabolism. Glycolaldehyde can be further catalyzed to form glycolic acid by lactaldehyde dehydrogenase.

Wild-Type E.coli K-12 can not directly use D-arabinose as a sole source of carbon and energy; hence, E.coli uses the enzymes of the fucose degradation pathway to degrade D-arabinose for further utilization. D-arabinose can be metabolized to form dihydroxy-acetone phosphate for entering the central metabolism. Glycolaldehyde can be further catalyzed to form glycolic acid by lactaldehyde dehydrogenase.

Ethylene glycol, or 1,2-ethanediol, is used to produce substances such as plastics, solvents, surfactants, explosives and cosmetics. Many of these are discarded into waste treatment and landfills. Both aerobic and anaerobic microorganisms can degrade ethylene glycol. While ethylene glycol cannot be used as a carbon source by wild-type E.coli, it can be utilized by isolated mutant strains. These strains contain two regulatory mutations: a mutation that increases propanediol oxidoreductase levels which functions to metabolize propanediol, and increased activity of Glycolaldehyde dehydrogenase to produce glycolate from glycolaldehyde.

Ethylene glycol, or 1,2-ethanediol, is used to produce substances such as plastics, solvents, surfactants, explosives and cosmetics. Many of these are discarded into waste treatment and landfills. Both aerobic and anaerobic microorganisms can degrade ethylene glycol. While ethylene glycol cannot be used as a carbon source by wild-type E.coli, it can be utilized by isolated mutant strains. These strains contain two regulatory mutations: a mutation that increases propanediol oxidoreductase levels which functions to metabolize propanediol, and increased activity of Glycolaldehyde dehydrogenase to produce glycolate from glycolaldehyde.