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Pathway Description
Trehalose Degradation I (Low Osmolarity)
Escherichia coli
Category:
Metabolite Pathway
Sub-Category:
Metabolic
Created: 2015-10-13
Last Updated: 2019-08-13
In E.coli, trehalose can be only synthesized with high osmolarity, and if the osmolarity is low, then the source of trehalose can be only obtained from external via transportation with trehalose PTS permease. However, sugar can be degraded with both low or high osmolarity in E.coli. Glucokinase can phosphorylate free gluocose into glucose-6-phosphate and both glucose-6-phosphate moieties enter glycolysis.
References
Trehalose Degradation I (Low Osmolarity) References
Klein W, Horlacher R, Boos W: Molecular analysis of treB encoding the Escherichia coli enzyme II specific for trehalose. J Bacteriol. 1995 Jul;177(14):4043-52.
Pubmed: 7608078
Rimmele M, Boos W: Trehalose-6-phosphate hydrolase of Escherichia coli. J Bacteriol. 1994 Sep;176(18):5654-64. doi: 10.1128/jb.176.18.5654-5664.1994.
Pubmed: 8083158
Burland V, Plunkett G 3rd, Sofia HJ, Daniels DL, Blattner FR: Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. Nucleic Acids Res. 1995 Jun 25;23(12):2105-19. doi: 10.1093/nar/23.12.2105.
Pubmed: 7610040
Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y: The complete genome sequence of Escherichia coli K-12. Science. 1997 Sep 5;277(5331):1453-62. doi: 10.1126/science.277.5331.1453.
Pubmed: 9278503
Meyer D, Schneider-Fresenius C, Horlacher R, Peist R, Boos W: Molecular characterization of glucokinase from Escherichia coli K-12. J Bacteriol. 1997 Feb;179(4):1298-306. doi: 10.1128/jb.179.4.1298-1306.1997.
Pubmed: 9023215
Yamamoto Y, Aiba H, Baba T, Hayashi K, Inada T, Isono K, Itoh T, Kimura S, Kitagawa M, Makino K, Miki T, Mitsuhashi N, Mizobuchi K, Mori H, Nakade S, Nakamura Y, Nashimoto H, Oshima T, Oyama S, Saito N, Sampei G, Satoh Y, Sivasundaram S, Tagami H, Horiuchi T, et al.: Construction of a contiguous 874-kb sequence of the Escherichia coli -K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features. DNA Res. 1997 Apr 28;4(2):91-113. doi: 10.1093/dnares/4.2.91.
Pubmed: 9205837
De Reuse H, Danchin A: The ptsH, ptsI, and crr genes of the Escherichia coli phosphoenolpyruvate-dependent phosphotransferase system: a complex operon with several modes of transcription. J Bacteriol. 1988 Sep;170(9):3827-37. doi: 10.1128/jb.170.9.3827-3837.1988.
Pubmed: 2457575
De Reuse H, Roy A, Danchin A: Analysis of the ptsH-ptsI-crr region in Escherichia coli K-12: nucleotide sequence of the ptsH gene. Gene. 1985;35(1-2):199-207. doi: 10.1016/0378-1119(85)90172-6.
Pubmed: 2411636
Saffen DW, Presper KA, Doering TL, Roseman S: Sugar transport by the bacterial phosphotransferase system. Molecular cloning and structural analysis of the Escherichia coli ptsH, ptsI, and crr genes. J Biol Chem. 1987 Nov 25;262(33):16241-53.
Pubmed: 2960675
Klein W, Horlacher R, Boos W: Molecular analysis of treB encoding the Escherichia coli enzyme II specific for trehalose. J Bacteriol. 1995 Jul;177(14):4043-52. doi: 10.1128/jb.177.14.4043-4052.1995.
Pubmed: 7608078
Yang Y, Zhao G, Winkler ME: Identification of the pdxK gene that encodes pyridoxine (vitamin B6) kinase in Escherichia coli K-12. FEMS Microbiol Lett. 1996 Jul 15;141(1):89-95. doi: 10.1111/j.1574-6968.1996.tb08368.x.
Pubmed: 8764513
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