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L-Arabinose Degradation I
Last Updated: 2018-12-22
Because L-arabinose enters E. coli either by a low-affinity proton-driven transporter (AraE) or a high-affinity ATP-driven system (AraFGH), its first intracellular form is unphosphorylated. Then an isomerase and a kinase convert it to L-ribulose-5-phosphate. An epimerase converts L-ribulose-5-phosphate to D-xylulose-5-phosphate, an intermediate of the pentose phosphate pathway, which thereby flows through the pathways of central metabolism to satisfy the cell's need for precursor metabolites, reducing power, and metabolic energy. (EcoCyc)
L-Arabinose Degradation I References
Fritz G, Megerle JA, Westermayer SA, Brick D, Heermann R, Jung K, Radler JO, Gerland U: Single cell kinetics of phenotypic switching in the arabinose utilization system of E. coli. PLoS One. 2014 Feb 26;9(2):e89532. doi: 10.1371/journal.pone.0089532. eCollection 2014.Pubmed: 24586851
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