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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 281144 results

SMP0071784

Pw072800 View Pathway
Metabolite

Phosphatidylethanolamine Biosynthesis PE(20:0/20:1(11Z))

Arabidopsis thaliana

  • Matched Description: cell membranes, and contrary to phosphatidylcholine, it is concentrated with phosphatidylserine in … clarity. Instead, they are indicated with a dark green colour and appear to be free floating in the … dehydrogenase [NAD(+)] catalyzes the interconversion of glycerone phosphate (from glycolysis) and glycerol 3 … catalyzes the synthesis of phosphatidylserine from L-serine and a CDP-diacylglycerol. Last
  • Matched Compounds: DG(20:0/20:1(11Z)/0:0) … PE(20:0/20:1(11Z)) … PA(20:0/20:1(11Z)) … LPA(20:0/0:0) … CDP-DG(20:0/20:1(11Z))
  • Matched Compound Synonyms: Dag(20:0/20:1) … Dag(20:0/20:1n9) … Dag(20:0/20:1w9) … Dg(20:0/20:1) … Dg(20:0/20:1n9)

  • Metabolic

    SMP0125788

    Pw127355 View Pathway
    Metabolite

    Vitamin A Deficiency

    Homo sapiens

  • Matched Description: the chemical reaction where the two substrates are beta-carotene and O2, whereas its product is … retinal. A defect in this enzyme results in decrease of levels of retinal and vitamin A in serum; Signs … and symptoms include night blindness, poor adaptation to darkness, dry skin and hair.
  • Matched Protein Synonyms: All-trans and 9-cis retinol dehydrogenase … PPAR-alpha-regulated and starvation-induced gene protein
  • Matched Compound Synonyms: 4-oh-retinoate … 4-oh-retinoic acid

  • Disease

    SMP0000037

    Pw000029 View Pathway
    Metabolite

    Lysine Degradation

    Homo sapiens

  • Matched Description: The degradation of L-lysine happens in liver and it is consisted of seven reactions. L-Lysine is … transporter 2. L-Lysine can also be obtained from biotin metabolism. L-Lysine and oxoglutaric acid will … synthase, and then, mitochondrial alpha-aminoadipic semialdehyde synthase will further breaks … saccharopine down to allysine and glutamic acid. Allysine will be degraded to form aminoadipic acid through … further catalyzed to form glutaryl-CoA, and glutaryl-CoA converts to crotonoyl-CoA, and crotonoyl-CoA
  • Matched Protein Synonyms: Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase … Dehydrogenase E1 and transketolase domain-containing protein 1
  • Matched Compound Synonyms: H-lys-oh … 3-oh-butyryl-coa … 3-oh-butyryl-coenzyme a … H-lys-oh … H-lys-oh

  • Metabolic

    SMP0125703

    Pw127270 View Pathway
    Metabolite

    2-Aminoadipic 2-Oxoadipic Aciduria

    Homo sapiens

  • Matched Description: disease is characterized by a large accumulation of 2-oxoadipate and 2-hydroxyadipate in the urine … , muscular hypotonia, and epilepsy. However, most cases are asymptomatic.
  • Matched Protein Synonyms: Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase … Dehydrogenase E1 and transketolase domain-containing protein 1
  • Matched Compound Synonyms: H-lys-oh … 3-oh-butyryl-coa … 3-oh-butyryl-coenzyme a … [oh(oh)] … H-lys-oh

  • Disease

    SMP0000068

    Pw000045 View Pathway
    Metabolite

    Androgen and Estrogen Metabolism

    Homo sapiens

  • Matched Description: This pathway describes the inactivation and catabolism of male (androgen) and female (estrogen … ) hormones. Many steroid hormones are transformed by sulfatases, dehydrogenases and glucuronide … transferases to enhance their solubility and to facilitate their elimination. Inactivation means to convert … activity does happen in the kidneys. Inactive androgens and estrogens are mostly eliminated in the … urine. For this to happen, androgen and estrogen need to be converted to compounds that are less
  • Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD
  • Matched Compound Synonyms: 17-oh progesterone … (3beta)-3,17-dihydroxypregn-5-en-20-one … 5-pregnen-3beta,17alpha-diol-20-one … (3b)-3,17-dihydroxypregn-5-en-20-one … (3β)-3,17-dihydroxypregn-5-en-20-one

  • Metabolic

    SMP0124875

    Pw126379 View Pathway
    Metabolite

    Metabolism and Physiological Effects of Oxalic acid

    Homo sapiens

  • Matched Description: glycine and hydroxyproline catabolism and can be converted to oxalate. In humans, this process takes … place in the liver. Glycine and hydroxyproline comes from protein sources in the diet such as red meat … and eggs. Glycine Is converted into glyoxylate in the peroxisome by the enzyme d-amino acid oxidase … synthesize oxalate in the body. Although the specific reactions and enzymes involved are still … the blood and have toxic effects in other tissues. Oxalate can promote cardiovascular disease, neurotoxicity and inflammation.
  • Matched Proteins: Sodium- and chloride-dependent creatine transporter 1 … Sodium- and chloride-dependent transporter XTRP3
  • Matched Protein Synonyms: Solute carrier family 6 member 20 … Solute carrier family 6 member 20
  • Matched Compound Synonyms: Ammonia (conc 20% or greater) … [oh(oh)] … [oh(oh)]

  • Metabolic

    SMP0122609

    Pw123923 View Pathway
    Metabolite

    Phenylalanine Metabolism

    Drosophila melanogaster

  • Matched Description: or substrates that feed into catabolic processes like the citric acid cycle and glycolysis. L
  • Matched Compound Synonyms: 2-oxo-3-phenylpropanoic acid (mixture oxo and keto) … Ammonia (conc 20% or greater) … [oh(oh)]

  • Metabolic

    SMP0124478

    Pw125958 View Pathway
    Metabolite

    Ifosfamide Alkylating Agent Action Pathway

    Homo sapiens

  • Matched Description: , acrolein is produced which is a potent lung irritant and causes hemorrhagic cystitis. Side effects of … ifosfamide is myelosuppression, immunosuppression and hemorrhagic cystitis (caused by acrolein).
  • Matched Protein Synonyms: Cytochrome P450 MP-20
  • Matched Compound Synonyms: Magnacide h and b

  • Drug Action

    SMP0000356

    Pw000059 View Pathway
    Metabolite

    17-beta Hydroxysteroid Dehydrogenase III Deficiency

    Homo sapiens

  • Matched Description: pseudohermaphroditism with gynecomastia (MPH), is as rare inborn error of metabolism (IEM) and autosomal … recessive disorder of the androgen and estrogen metabolism pathway. It is caused by a mutation in the … accumulation of androstenedione and dehydroepiandrosterone in the body, as well as a lack of testosterone … puberty, where testosterone is produced outside of the gonads. Symptoms include infertility and external
  • Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD
  • Matched Compound Synonyms: 17-oh progesterone … (3beta)-3,17-dihydroxypregn-5-en-20-one … 5-pregnen-3beta,17alpha-diol-20-one … (3b)-3,17-dihydroxypregn-5-en-20-one … (3β)-3,17-dihydroxypregn-5-en-20-one

  • Disease

    SMP0000590

    Pw000566 View Pathway
    Metabolite

    Ibuprofen Metabolism Pathway

    Homo sapiens

  • Matched Description: Ibuprofen is a very common NSAID drug used to treat pain and inflammation. This includes headaches … , muscle pain and fever. It is sold under the brand name Advil or Motrin. Ibuprofen is typically … prostaglandin G/H synthase (COX). These enzymes are available as COX1 and COX2, and are encoded by … PTGS1 (COX1) and PTGS2 (COX2). Ibuprofen may also inhibit fatty acid amide hydrolase (FAAH), which
  • Matched Protein Synonyms: Cytochrome P450 MP-20 … Cytochrome P450 MP-20
  • Matched Compound Synonyms: [oh(oh)]

  • Drug Metabolism