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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 517624 results

SMP0125788

Pw127355 View Pathway
Metabolite

Vitamin A Deficiency

Homo sapiens

  • Matched Description: the chemical reaction where the two substrates are beta-carotene and O2, whereas its product is … retinal. A defect in this enzyme results in decrease of levels of retinal and vitamin A in serum; Signs … and symptoms include night blindness, poor adaptation to darkness, dry skin and hair.
  • Matched Protein Synonyms: All-trans and 9-cis retinol dehydrogenase … PPAR-alpha-regulated and starvation-induced gene protein
  • Matched Compound Synonyms: 4-oh-retinoate … 4-oh-retinoic acid

  • Disease

    SMP0000590

    Pw000566 View Pathway
    Metabolite

    Ibuprofen Metabolism Pathway

    Homo sapiens

  • Matched Description: Ibuprofen is a very common NSAID drug used to treat pain and inflammation. This includes headaches … , muscle pain and fever. It is sold under the brand name Advil or Motrin. Ibuprofen is typically … prostaglandin G/H synthase (COX). These enzymes are available as COX1 and COX2, and are encoded by … PTGS1 (COX1) and PTGS2 (COX2). Ibuprofen may also inhibit fatty acid amide hydrolase (FAAH), which
  • Matched Protein Synonyms: Cytochrome P450 MP-20 … Cytochrome P450 MP-20
  • Matched Compound Synonyms: [oh(oh)]

  • Drug Metabolism

    SMP0000356

    Pw000059 View Pathway
    Metabolite

    17-beta Hydroxysteroid Dehydrogenase III Deficiency

    Homo sapiens

  • Matched Description: pseudohermaphroditism with gynecomastia (MPH), is as rare inborn error of metabolism (IEM) and autosomal … recessive disorder of the androgen and estrogen metabolism pathway. It is caused by a mutation in the … accumulation of androstenedione and dehydroepiandrosterone in the body, as well as a lack of testosterone … puberty, where testosterone is produced outside of the gonads. Symptoms include infertility and external
  • Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD
  • Matched Compound Synonyms: 17-oh progesterone … (3beta)-3,17-dihydroxypregn-5-en-20-one … 5-pregnen-3beta,17alpha-diol-20-one … (3b)-3,17-dihydroxypregn-5-en-20-one … (3β)-3,17-dihydroxypregn-5-en-20-one

  • Disease

    SMP0125782

    Pw127349 View Pathway
    Metabolite

    Aromatase Deficiency

    Homo sapiens

  • Matched Description: Aromatase deficiency is a rare inborn error of metabolism (IEM) and autosomal recessive disorder of … converts androgens to estrogens which is vital for bone growth and regulation of blood sugar levels … . Symptoms of decrease in estrogen and increase androgens such as testosterone can cause impaired female … sexual development, unusual bone growth, insulin resistance, and a variety of other symptoms. It … presents with virilization of pregnant mothers during the antenatal period, and virilization of female
  • Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD
  • Matched Compound Synonyms: 17-oh progesterone … (3beta)-3,17-dihydroxypregn-5-en-20-one … 5-pregnen-3beta,17alpha-diol-20-one … (3b)-3,17-dihydroxypregn-5-en-20-one … (3β)-3,17-dihydroxypregn-5-en-20-one

  • Disease

    SMP0728344

    Pw766123 View Pathway
    Metabolite

    Ovarian Steroidogenesis

    Homo sapiens

  • Matched Description: , specifically within theca and granulosa cells of the ovary. The process begins when luteinizing hormone (LH … . Androstenedione is transported to the granulosa cells, where it is converted into estrone and estradiol, the … pathway that links LH stimulation to estrogen production and release.
  • Matched Protein Synonyms: 20 alpha-hydroxysteroid dehydrogenase … 20-alpha-HSD
  • Matched Compound Synonyms: 20-iso-cholesterol … 20-epi-cholesterol … 20-iso-cholesterol … (3b)-3-hydroxy-pregn-5-en-20-one … 3-hydroxypregn-5-en-20-one

  • Physiological

    SMP0000074

    Pw000164 View Pathway
    Metabolite

    Retinol Metabolism

    Homo sapiens

  • Matched Description: Retinol is part of the vitamin A family, and is known as vitamin A1, and in a dietary context it is … sources, with the highest concentrations coming from animal liver, with other sources being fish and … acid form, and reinyl ester, its ester form. Additionally, herbivores and omnivores can obtain … provitamin A from things such as alpha-, beta- and gamma-carotene, which can be converted to retinol as … -acyltransferase 1 and acyl-CoA wax akcohol acyltransferase 1 which both use acetyl-CoA as a reactant and
  • Matched Protein Synonyms: All-trans and 9-cis retinol dehydrogenase … PPAR-alpha-regulated and starvation-induced gene protein
  • Matched Compound Synonyms: 4-oh-retinoate … 4-oh-retinoic acid

  • Metabolic

    SMP0000480

    Pw000171 View Pathway
    Metabolite

    Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids

    Homo sapiens

  • Matched Description: Beta-oxidation is the major degradative pathway for fatty acid esters in humans. Fatty acids and … , regulators of enzymes and membrane channels, ligands for nuclear receptors, precursor molecules for … hormones, and signalling molecules. Beta-oxidation occurs in the peroxisomes and mitochondria, the … -CoA in the peroxisomes and then transported to the mitochondria for the remainder of the oxidation … produce a fatty acyl-CoA. Short and medium chain fatty acids can enter the mitochondria directly via
  • Matched Protein Synonyms: Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase … Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase
  • Matched Compound Synonyms: 3-oh-butyryl-coa … 3-oh-butyryl-coenzyme a

  • Metabolic

    SMP0000336

    Pw000210 View Pathway
    Metabolite

    Vitamin A Deficiency

    Homo sapiens

  • Matched Description: the chemical reaction where the two substrates are beta-carotene and O2, whereas its product is … retinal. A defect in this enzyme results in decrease of levels of retinal and vitamin A in serum; Signs … and symptoms include night blindness, poor adaptation to darkness, dry skin and hair.
  • Matched Protein Synonyms: All-trans and 9-cis retinol dehydrogenase … PPAR-alpha-regulated and starvation-induced gene protein
  • Matched Compound Synonyms: 4-oh-retinoate … 4-oh-retinoic acid

  • Disease

    SMP0000568

    Pw000544 View Pathway
    Metabolite

    Short-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency (HADH)

    Homo sapiens

  • Matched Description: deficiency, is a rare inborn error of metabolism (IEM) and autosomal recessive disorder of the … responsible for the beta-oxidation of 3-hydroxyhexanoyl-CoA and 3-hydroxybutyryl-CoA into 3 … -oxohexanoyl-CoA and acetoacetyl-CoA respectively. Symptoms of HADH deficiency include hypoglycemia, as well as … vomiting, diarrhea and seizures. Treatment with diazoxide, a potassium channel activator, has been
  • Matched Protein Synonyms: Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase … Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase
  • Matched Compound Synonyms: 3-oh-butyryl-coa … 3-oh-butyryl-coenzyme a

  • Disease

    SMP0071785

    Pw072801 View Pathway
    Metabolite

    Phosphatidylethanolamine Biosynthesis PE(20:0/20:1(13Z))

    Arabidopsis thaliana

  • Matched Description: cell membranes, and contrary to phosphatidylcholine, it is concentrated with phosphatidylserine in … clarity. Instead, they are indicated with a dark green colour and appear to be free floating in the … dehydrogenase [NAD(+)] catalyzes the interconversion of glycerone phosphate (from glycolysis) and glycerol 3 … catalyzes the synthesis of phosphatidylserine from L-serine and a CDP-diacylglycerol. Last
  • Matched Compounds: DG(20:0/20:1(13Z)/0:0) … PE(20:0/20:1(13Z)) … PA(20:0/20:1(13Z)) … LysoPA(20:0/0:0) … CDP-DG(20:0/20:1(13Z))
  • Matched Compound Synonyms: Dg(20:0/20:1) … Dg(20:0/20:1n7) … Dg(20:0/20:1w7) … Dag(20:0/20:1(13z)) … Dag(20:0/20:1)

  • Metabolic