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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 268651 results

SMP0174915

Pw176601 View Pathway
Metabolite

Acrivastine H1 Antihistamine Smooth Muscle Relaxation Action Pathway

Homo sapiens

  • Matched Description: such as sneezing, rhinorrhea, pruritus, lacrimation, and nasal congestion. H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … vessels to constrict dilated blood vessels, and in smooth muscles of lungs and intestines to relax … and are administered to attenuate inflammatory process in order to treat conditions such as allergic

  • Drug Action

    SMP0174912

    Pw176598 View Pathway
    Metabolite

    Antazoline H1 Antihistamine Smooth Muscle Relaxation Action Pathway

    Homo sapiens

  • Matched Description: Antazoline is an antihistamine agent used for the symptomatic treatment of nasal congestion and … receptor and are administered to attenuate inflammatory process in order to treat conditions such as … allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors in T … -cells to inhibit the immune response, in blood vessels to constrict dilated blood vessels, and in … smooth muscles of lungs and intestines to relax those muscles. H1-antihistamines interfere with the

  • Drug Action

    SMP0174907

    Pw176593 View Pathway
    Metabolite

    Pheniramine H1 Antihistamine Smooth Muscle Relaxation Action Pathway

    Homo sapiens

  • Matched Description: Pheniramine is an antihistamine used to treat allergic rhinitis and pruritus. H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … , and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit the immune response, in … blood vessels to constrict dilated blood vessels, and in smooth muscles of lungs and intestines to … receptor and are administered to attenuate inflammatory process in order to treat conditions such as

  • Drug Action

    SMP0124522

    Pw126003 View Pathway
    Metabolite

    Carvedilol Action Pathway

    Homo sapiens

  • Matched Description: through hepatic portal circulation, and enters the bloodstream and travels to act on cardiomyocytes … . Carvedilol is a racemic mixture where the S(-) enantiomer is a beta adrenoceptor blocker and the R … (+) enantiomer is both a beta and alpha-1 adrenoceptor blocker. In bronchial and vascular smooth … production, which then activates SRC and nitric oxide synthase, its inhibition causes the inhibition … of cAMP, PKA, SRC and nitric oxide synthase signaling. Following this chain of reactions, we see

  • Drug Action

    SMP0126187

    Pw127772 View Pathway
    Metabolite

    Bopindolol Action Pathway (New)

    Homo sapiens

  • Matched Description: Bopindolol is a non-cardioselective beta blocker and the ester prodrug of pinolol. It can be … administered orally, where it passes through hepatic portal circulation, and enters the bloodstream and … travels to act on cardiomyocytes. In bronchial and vascular smooth muscle, bopindolol can compete with … activates SRC and nitric oxide synthase, its inhibition causes the inhibition of cAMP, PKA, SRC and nitric … Caspase 3 and Caspase 9. This Caspase cascade leads to cell apoptosis. The net result of all these

  • Drug Action

    SMP0174910

    Pw176596 View Pathway
    Metabolite

    Mepyramine H1 Antihistamine Smooth Muscle Relaxation Action Pathway

    Homo sapiens

  • Matched Description: , hypersensitivity reactions, and pruritic skin disorders. H1-antihistamines interfere with the agonist action of … histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act … blood vessels, and in smooth muscles of lungs and intestines to relax those muscles. H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate

  • Drug Action

    SMP0174937

    Pw176623 View Pathway
    Metabolite

    Cetirizine H1 Antihistamine Smooth Muscle Relaxation Action Pathway

    Homo sapiens

  • Matched Description: Cetirizine is a selective Histamine-1 antagonist drug used in allergic rhinitis and chronic … urticaria. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are … , allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit … the immune response, in blood vessels to constrict dilated blood vessels, and in smooth muscles of … lungs and intestines to relax those muscles. H1-antihistamines interfere with the agonist action of

  • Drug Action

    SMP0012048

    Pw012909 View Pathway
    Metabolite

    Glycine Betaine Biosynthesis II

    Arabidopsis thaliana

  • Matched Description: Glycine betaine biosynthesis I, beginning in the cytosol and ending in the peroxisome results in … osmotic stress, mutagenesis, and radiation-induced damage. First, serine decarboxylase (SDC) uses a … proton and a pyridoxal 5'-phosphate cofactor to catalyze the conversion of L-serine to ethanolamine … -phosphoethanolamine. Note that this is only the probable ethanolamine kinase in Arabidopsis thaliana and … requires further research to confirm its function. Steps 3, 4, and 5 are catalyzed by

  • Metabolic

    SMP0000668

    Pw000645 View Pathway
    Metabolite

    Bevantolol Action Pathway

    Homo sapiens

  • Matched Description: treat angina pectoris and hypertension. Bevantolol is an antagonist of beta-1 adrenoreceptors to … block the G protein signalling cascade and inhibit epinephrine induced sympathetic activation such as … stimulate beta-adrenergic receptors. This results in a decrease in preload and blood pressure.

  • Drug Action

    SMP0002017

    Pw002003 View Pathway
    Metabolite

    Ketogluconate Metabolism

    Escherichia coli

  • Matched Description: through a NADPH dependent 2,5-diketo-D-gluconate reductase resulting in the release of a NADP and 5 … resulting in the release of a NADP and a 2-keto-L-gulonate. The 2-keto-L-gulonate interacts with a NADPH 2 … -keto-L-gulonate reductase resulting in a NADP and a L-idonate. The L-idonate interacts with a NADP L … -idonate 5-dehydrogenase resulting in the release of hydrogen ion, a NADPH and a 5-dehydro-D … in the release of a NADP and a D-gluconate. The other way to produce D-gluconate is by having 2,5

  • Metabolic