SMP0126930
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Norfloxacin Action Pathway
Haemophilus influenzae
Matched Description: -positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in … the urine.
Norfloxacin inhibits DNA gyrase (topoisomerase II) and topoisomerase IV. These proteins … prevent supercoiling in bacterial DNA. The inhibition of DNA gyrase (topoisomerase II) and
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SMP0124537
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Torasemide Action Pathway (New)
Homo sapiens
Matched Description: Torasemide is a loop diuretic drug, administered orally or intravenously to treat hypertension and … loop of henle contains the Na+/K+ ATPase, Cl- channel and K+/Cl- co-transporter which are essential … for the function for ion and water reabsorption. The Na+/K+ ATPase pumps Na+ from the cell into the … peritubular fluid and K+ from the peritubular fluid into the cell. The K+/Cl- co-transporter moves K … + and Cl- from the cell into the peritubular fluid and the Cl- channel transports Cl- from the cell
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SMP0126775
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Turoctocog Alfa Action Pathway
Homo sapiens
Matched Description: Turoctocog alfa is a recombinant factor VIII, also known as Novoeight and Zonovate, used to treat … administered intravenously and acts similarly to coagulation factor VIII, forming a complex with IX in order … to activate factor X leading to a blood clot forming. Turoctocog alfa allows the missing factor coagulation VIII to be replaced and restore blood clotting.
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SMP0126221
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Practolol Action Pathway (New)
Homo sapiens
Matched Description: through hepatic portal circulation, and enters the bloodstream and travels to act on cardiomyocytes. In … bronchial and vascular smooth muscle, practolol can compete with epinephrine for beta-2 adrenergic … synthesis, which in turn activates PKA production, which then activates SRC and nitric oxide synthase, its … inhibition causes the inhibition of cAMP, PKA, SRC and nitric oxide synthase signaling. Following … , the inhibition of SRC in essence causes the activation of Caspase 3 and Caspase 9. This Caspase
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SMP0174908
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Methapyrilene H1 Antihistamine Smooth Muscle Relaxation Action Pathway
Homo sapiens
Matched Description: histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on … vessels, and in smooth muscles of lungs and intestines to relax those muscles.
H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … , and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit the immune response, in
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SMP0174913
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Chloropyramine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
Homo sapiens
Matched Description: action of histamine at the H1 receptor and are administered to attenuate inflammatory process in … order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1 … constrict dilated blood vessels, and in smooth muscles of lungs and intestines to relax those muscles.
H1 … -antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered … conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit the
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SMP0174916
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Ebastine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
Homo sapiens
Matched Description: at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 … vessels, and in smooth muscles of lungs and intestines to relax those muscles.
H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and
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SMP0174896
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Carbinoxamine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
Homo sapiens
Matched Description: histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on … vessels, and in smooth muscles of lungs and intestines to relax those muscles.
H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … , and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit the immune response, in
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SMP0174928
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Quetiapine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
Homo sapiens
Matched Description: at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 … vessels, and in smooth muscles of lungs and intestines to relax those muscles
H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and
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SMP0174921
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Methdilazine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
Homo sapiens
Matched Description: histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 … vessels, and in smooth muscles of lungs and intestines to relax those muscles.
H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … , and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit the immune response, in
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