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Matched Description: analgesic and to treat opioid dependence. Levomethadyl Acetate is metabolized by cytochrome P450 3A4 in … two N-demethylation reactions to nor-levomethadyl acetate (nor-LAAM) and subsequently to dinor-levomethadyl acetate (dinor-LAAM).

Matched Description: norepinephrine and serotonin reuptake in the brain. It does so by competing for the same binding site as … norepinephrine on the sodium-dependent noradraneline transporter (SLC6A2) and by competing with … concentrations of both norepinephrine and serotonin in their respective synapses and reverses the state of low … norepinephrine and serotonin have also been shown to have long-term neuromodulatory effects. Binding of these … the nucleus and affects transcription of brain-derived neurotrophic factor (BDNF). BDNF

Matched Description: bactericidal and binds to specific penicillin-binding proteins, thereby inhibiting transpeptidation during … instability of bacterial cell wall and results in cell lysis. Cyclacillin is beta-lactamase susceptible.

Matched Description: mesolimbic dopaminergic D1 and D2 receptors in the brain; blocks alpha-adrenergic effect, depresses the … release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating … system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis … , pediatric behavioral disorders, and geriatric psychoneurotic manifestations. Positive symptoms are … symptoms. Thioridazine is classified as a low potency first-generation antipsychotic, and as such, is

Matched Description: neurotransmitters for binding to beta(1)-adrenergic receptors in the heart and the beta(2)-receptors in the … vascular and bronchial smooth muscle. This leads to diminished actions of catecholamines, which normally … bind to adrenergic receptors and exert sympathetic effects leading to an increase in blood pressure … and heart rate. Beta(1)-receptor blockade by timolol leads to a decrease in both heart rate and … cardiac output during rest and exercise, and a decrease in both systolic and diastolic blood pressure

Matched Description: prevent the spread of HIV. When HIV infects a cell, the virus first binds and fuses with the cell … , releasing its nucleocapsid containing its RNA and reverse transcriptase into the cytosol of the cell. The … complex and translation occurs to produce viral proteins. These viral proteins are assembled and new HIV … viruses bud from the cell. Abacavir enters the cell and inhibits the activity of HIV-1 reverse … transcriptase by binding to a non-catalytic site of the enzyme in a reversible and non-competitive

Matched Description: epilepticus and prevention and treatment of seizures occurring during neurosurgery. It can be found … under the brand names Cerebyx and Sesquient. Fosphenytoin is a water-soluble phenytoin prodrug used … brain that cause seizures. Its main mechanism is to block frequency-dependent, use-dependent and … voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials … . Fosphenytoin is a prodrug of phenytoin and accordingly, its anticonvulsant effects are attributable to

Matched Description: gyrase (topoisomerase II) and topoisomerase IV. These proteins prevent supercoiling in bacterial DNA … . The inhibition of DNA gyrase (topoisomerase II) and topoisomerase IV causes supercoiling of the bacterial DNA. This prevents DNA replication.

Matched Description: DNA gyrase (topoisomerase II) and topoisomerase IV. These proteins prevent supercoiling in bacterial … DNA. The inhibition of DNA gyrase (topoisomerase II) and topoisomerase IV causes supercoiling of the bacterial DNA. This prevents DNA replication.

Matched Description: remove head lice. It acts on insects and due to its relative dosage compared to a human, the lice … having their acetylcholinesterase inhibited leading to muscle spasm and eventually death.