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Matched Description: hypotensive states and as an adjunct treatment during cardiac arrest. It can be found under the brand name … Levophed. Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central … and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic … sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus … . It is also found in plants and is used pharmacologically as a sympathomimetic. Noradrenaline acts

Matched Description: Protein C is also known under brand names such as Balfaxar, Beriplex, Ceprotin, Kcentra and … Octaplex used to treat purpura fulminans and or coumarin-induced skin necrosis. Protein C is an endogenous … and VIII, decreasing clot formation. Due to its anticoagulant nature herbs and supplements with … similar activity should be avoided such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba.

Matched Description: Apixaban is an oral anticoagulant drug that competitively inhibits free and bound coagulation … strokes or systemic embolism. Used in the treatment and prevention of recurrent thromboembolic diseases … , such as deep vein thrombosis and pulmonary embolisms. Apixaban is metabolized by both CYP3A4 and P … -glycoprotein (P-gp) and is known to increase in the blood when these are inhibited. Apixaban enters

Matched Description: , P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis … accumulate toxic heme, killing the parasite. Chloroquine passively diffuses through cell membranes and into … endosomes, lysosomes, and Golgi vesicles; where it becomes protonated, trapping the chloroquine in … the organelle and raising the surrounding pH. The raised pH in endosomes, prevent virus particles … from utilizing their activity for fusion and entry into the cell.

Matched Description: , including VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). Lenvatinib also inhibits other RTKs, such … as fibroblast growth factor receptors (FGFR1, 2, 3, and 4), the platelet-derived growth factor … receptor alpha (PDGFRα), KIT, and RET, all of which play crucial roles in processes like angiogenesis … , tumor growth, and cancer progression. Its approved indications include metastatic thyroid cancer … , advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma

Matched Description: neurotransmitters like catecholamines to bind beta(1)-adrenergic receptors of the heart and … vascular smooth muscle. Propranolol binding reduces resting heart rate, cardiac output, blood pressure and … , anxiety and tremor. Propranolol also competes for beta(2)-adrenergic receptors on bronchial and vascular smooth muscles.

Matched Description: booster. Ritonavir is a potent CYP3A inhibitor that increases peak and trough plasma drug … concentrations of other protease inhibitors such as Paritaprevir and overall drug exposure. Ritonavic inhibits … the HIV viral proteinase enzyme that normally cleaves the structural and replicative proteins that … arise from major HIV genes, such as gag and pol. The HIV virus binds and penetrates the host cell … and is integrated into the host DNA via integrase. The DNA is then transcribed, creating viral mRNA

Matched Description: Reviparin is a low molecular weight heparin derived from a pig's intestinal mucus and used to prevent thromboembolism.

Matched Description: Remifentanil is a pharmacologically-active, synthetic, small molecule derived from fentanyl and … receptors which are inhibitory G-coupled protein receptors and lead to the inhibition of adenylate … cyclase and decrease in cAMP production. Analgesia, anesthesia, and respiratory depression are a

Matched Description: as Retavase that is used in emergencies such as myocardial infarction, ischemic stroke and … pulmonary emboli. Reteplase is administered intravenously and travels through the bloodstream and acts on … goes to act on the fibrin matrix and degrades it into its products eliminating the blood clot.