SMP0349093
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Methylphosphonate Degradation I
Escherichia coli UMN026
Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.
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SMP0349100
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Methylphosphonate Degradation I
Escherichia coli O103:H2 str. 12009
Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.
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SMP0349095
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Methylphosphonate Degradation I
Escherichia coli IAI1
Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.
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SMP0333257
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Methylphosphonate Degradation I
Citrobacter youngae ATCC 29220
Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.
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SMP0121018
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Pancreas Function - Beta Cell
Homo sapiens
Matched Description: Beta cells are found in pancreatic islet cells and their main function is to release insulin … . Insulin counteracts glucagon and functions to maintain glucose homeostasis when glucose levels are high … on extracellular glucose levels, and intracellular calcium levels and/or various proteins that … outside of the insulin granule to tether, dock, and fuse with the beta cell membrane. Insulin is then … cell membrane and trigger a G protein cascade. This eventually leads to the activation of inositol
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SMP0126905
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Gq Adrenergic Smooth Muscle Contraction
Rattus norvegicus
Matched Description: phosphatidylinositol 4,5-bisphosphate (PIP2) to diacyl glycerol (DAG) and inositol trisphosphate … different pathways. Gq proteins rely on enzymes of the phospholipase C family (PLC), while Gs and Gi … proteins respectively stimulate and inhibit adenylate cyclase (AC) and thus act upon the amount of … to specific stimuli in smooth muscle, the intracellular concentration of Ca2+ increases, and this … -bisphosphate to catalyze the formation of two potent second messengers: inositol trisphosphate (IP3) and
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SMP0012067
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cis-Zeatin-N-Glucoside Biosynthesis
Arabidopsis thaliana
Matched Description: , or cytokinesis, in plant roots and shoots. They are involved primarily in cell growth and … differentiation, but also affect apical dominance, axillary bud growth, and leaf senescence. Zeatin is an … prenylation of tRNA molecules and dimethylallyl diphosphate precursors provided through the mevalonate … cytokinins. N-glucosylation is irreversible and is hypothesized to be involved with detoxification. Only … the enzymes that catalyze the first and last steps of this pathway have been elucidated (all
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SMP0130467
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Dopamine Action Pathway
Bos taurus
Matched Description: many heart problems and diseases. Dopamine is a precursor to norepinephrine in the sympathetic … membrane, causing the channels to open and allow Ca2+ into the cell. This causes a high concentration … + binds to troponin to cause cardiac muscle contractions and therefore, an increased heart rate. This … helps conditions like Arrhythmia, myocardial infarctions, open-heart surgery, and trauma-induced … through norepinephrine in noradrenergic neurons outside the brain, and especially in the heart. Low
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SMP0130482
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Nicotinic Acetylcholine
Rattus norvegicus
Matched Description: . They are found in the central and peripheral nervous system, muscle, and many other tissues of many … outgoing signals from the presynaptic to the postsynaptic cells within the sympathetic and … parasympathetic nervous system, and (2) they are the receptors found on skeletal muscle that receive … inflammatory processes and signal through distinct intracellular pathways. The nicotinic receptors are … , sodium enters the cell and potassium exits. The net flow of positively charged ions is inward. The nAChR
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SMP0428383
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Galactose Degradation/Leloir Pathway
Prevotella albensis DSM 11370 = JCM 12258
Matched Description: , galactose-1-phosphate uridylyltransferase and UDP-glucose 4-epimerase. Beta-D-galactose can be uptaken … degradation involving a lactose permease to uptake lactose from the environment and a beta-galactosidase … lactose interacts with water through a beta-galactosidase resulting in a beta-D-glucose and beta-D … -D-glucose 1-phosphate) interacts with UTP and a hydrogen ion in order to produce a uridine … output a glucose-1-phosphate and a uridine diphosphate galactose. The glucose -1-phosphate is
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