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Matched Description: , postherpetic neuralgia, and partial-onset seizures. Gabapentin acts at the nerve terminals of … neurotransmitters like glutamate contribute to neuropathic pain and seizures. The role of gabapentin is to … influx is prevented and the release of glutamate neurotransmitter does not occur.

Matched Description: 5-HT1B and 5-HT1D receptors. It is structurally distinct from, but pharmacologically related to … channel activity and has no significant affinity for benzodiazepine binding sites. Frovatriptan is … believed to act on extracerebral, intracranial arteries and to inhibit excessive dilation of these

Matched Description: intramuscularly. It travels through the blood to the target cells in the naltrexone pathway and to the … remainder is metabolized into 6-beta-naltrexol and other minor metabolites. Naltrexone and 6-beta

Matched Description: in significant quantities from the gastrointestinal tract and must be administered parenterally … (intramuscular or intravenous). The side effects are tinnitus, hearing loss, proteinuria, and renal … dysfunction. As Mycobacterium Tuberculosis enters several cell types (neutrophils, macrophages, and

Matched Description: decreases intracellular cAMP concentrations and blocks IP3-dependent release of Ca2+ from … . Additionally, receptor activation blocks phosphorylation of p42/p44 MAPK and decreases MAPK/ERK … kinase phosphorylation. Inhibition of MAPK appears to be mediated by c-Raf and B-Raf-dependent

Matched Description: Cabotegravir is an HIV-1 integrase inhibitor used for treatment and pre-exposure prophylaxis of HIV … host DNA. This prevents viral replication and further progression of the virus. It is used in … combination with reverse transcriptase inhibitors which further prevents viral replication and progression of the virus.

Matched Description: noradrenergic and dopaminergic pathways plays a critical role. Due to atomoxetine's noradrenergic activity … , it also has effects on the cardiovascular system such as increased blood pressure and tachycardia … synapses and in the brain in general. This will increase the activation of alpha-adrenergic

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.