Browsing Search Results

Matched Description: decreases intracellular cAMP concentrations and blocks IP3-dependent release of Ca2+ from … . Additionally, receptor activation blocks phosphorylation of p42/p44 MAPK and decreases MAPK/ERK … kinase phosphorylation. Inhibition of MAPK appears to be mediated by c-Raf and B-Raf-dependent

Matched Description: Cabotegravir is an HIV-1 integrase inhibitor used for treatment and pre-exposure prophylaxis of HIV … host DNA. This prevents viral replication and further progression of the virus. It is used in … combination with reverse transcriptase inhibitors which further prevents viral replication and progression of the virus.

Matched Description: noradrenergic and dopaminergic pathways plays a critical role. Due to atomoxetine's noradrenergic activity … , it also has effects on the cardiovascular system such as increased blood pressure and tachycardia … synapses and in the brain in general. This will increase the activation of alpha-adrenergic

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.

Matched Description: , which leads to decreased arterial smooth muscle contractility and subsequent vasoconstriction … , calmodulin couldn't form the calcium-bound calmodulin, which is required for binding and activating … cells and results in vasodilation, which ultimately lead to overall decresing in blood pressure.

Matched Description: inborn error of metabolism (IEM) and autosomal recessive disorder caused by either a homozygous or … generalized amino aciduria and marked galactosuria. Treatment usually includes galactose restricted … with galactokinase deficiency and classic galactosemia, patients with galactose epimerase deficiency

Matched Description: release of a hydrogen ion, a pyrophosphate and a alpha-Dribose-1-methylphosphonate 5-phosphate. The … and a 5-phospho-alpha-D-ribose 1,2-cyclic phosphate. This compound in turn gets degraded by a water … driven 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase resulting in the release of a hydrogen ion and a alpha-D-ribose 1,5-biphosphate.