SMP0406344
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Mannose Metabolism
Neisseria elongata subsp. glycolytica ATCC 29315
Matched Description: Escherichia coli can utilize D-mannose for its sole carbon and energy source. Alpha-D-mannose is … isomerase. D-fructose-6-phosphate is an intermediate of glycolysis and can enter the pathways of … phosphorylated aldohexoses (β-D-glucose-6-phosphate, D-mannose-6-phosphate) and phosphorylated ketohexoses (D … phosphomannomutase and mannose-1-phosphate guanylyltransferase. GDP-D-mannose produces GDP-L-fucose beginning … epimerase and reductase of GDP-4-dehydro-6-deoxy-D-mannose. L-fucose then enters the colanic acid building blocks biosynthesis pathway.
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SMP0407246
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Mannose Metabolism
Plesiomonas shigelloides 302-73
Matched Description: Escherichia coli can utilize D-mannose for its sole carbon and energy source. Alpha-D-mannose is … isomerase. D-fructose-6-phosphate is an intermediate of glycolysis and can enter the pathways of … phosphorylated aldohexoses (β-D-glucose-6-phosphate, D-mannose-6-phosphate) and phosphorylated ketohexoses (D … phosphomannomutase and mannose-1-phosphate guanylyltransferase. GDP-D-mannose produces GDP-L-fucose beginning … epimerase and reductase of GDP-4-dehydro-6-deoxy-D-mannose. L-fucose then enters the colanic acid building blocks biosynthesis pathway.
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SMP0407371
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Mannose Metabolism
Acinetobacter junii SH205
Matched Description: Escherichia coli can utilize D-mannose for its sole carbon and energy source. Alpha-D-mannose is … isomerase. D-fructose-6-phosphate is an intermediate of glycolysis and can enter the pathways of … phosphorylated aldohexoses (β-D-glucose-6-phosphate, D-mannose-6-phosphate) and phosphorylated ketohexoses (D … phosphomannomutase and mannose-1-phosphate guanylyltransferase. GDP-D-mannose produces GDP-L-fucose beginning … epimerase and reductase of GDP-4-dehydro-6-deoxy-D-mannose. L-fucose then enters the colanic acid building blocks biosynthesis pathway.
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SMP0407911
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Mannose Metabolism
Methylibium sp. Pch-M
Matched Description: Escherichia coli can utilize D-mannose for its sole carbon and energy source. Alpha-D-mannose is … isomerase. D-fructose-6-phosphate is an intermediate of glycolysis and can enter the pathways of … phosphorylated aldohexoses (β-D-glucose-6-phosphate, D-mannose-6-phosphate) and phosphorylated ketohexoses (D … phosphomannomutase and mannose-1-phosphate guanylyltransferase. GDP-D-mannose produces GDP-L-fucose beginning … epimerase and reductase of GDP-4-dehydro-6-deoxy-D-mannose. L-fucose then enters the colanic acid building blocks biosynthesis pathway.
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SMP0407792
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Mannose Metabolism
Phascolarctobacterium succinatutens YIT 12067
Matched Description: Escherichia coli can utilize D-mannose for its sole carbon and energy source. Alpha-D-mannose is … isomerase. D-fructose-6-phosphate is an intermediate of glycolysis and can enter the pathways of … phosphorylated aldohexoses (β-D-glucose-6-phosphate, D-mannose-6-phosphate) and phosphorylated ketohexoses (D … phosphomannomutase and mannose-1-phosphate guanylyltransferase. GDP-D-mannose produces GDP-L-fucose beginning … epimerase and reductase of GDP-4-dehydro-6-deoxy-D-mannose. L-fucose then enters the colanic acid building blocks biosynthesis pathway.
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SMP0407724
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Mannose Metabolism
[Clostridium] innocuum 2959
Matched Description: Escherichia coli can utilize D-mannose for its sole carbon and energy source. Alpha-D-mannose is … isomerase. D-fructose-6-phosphate is an intermediate of glycolysis and can enter the pathways of … phosphorylated aldohexoses (β-D-glucose-6-phosphate, D-mannose-6-phosphate) and phosphorylated ketohexoses (D … phosphomannomutase and mannose-1-phosphate guanylyltransferase. GDP-D-mannose produces GDP-L-fucose beginning … epimerase and reductase of GDP-4-dehydro-6-deoxy-D-mannose. L-fucose then enters the colanic acid building blocks biosynthesis pathway.
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SMP0002194
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Operon: Mannose Uptake Inactivation
Escherichia coli
Matched Description: transcription. However, if beta-D-fructofuranose 1-phosphate is present, it will bind to Cra and … , which prevents it from binding to the DNA, and stops the inhibition of the operon.
The first gene … in the operon, manX, encodes the PTS system mannose-specific EIIAB component protein with an A and B … domain that are linked. The protein is a dimer in the cell, and is found in the inner membrane of … permease complex. The protein products of manX and manY are required for lambda phage infection of the
Gene Regulatory
Transport/Degradation
Cellular Response
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SMP0126264
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Phenytoin Action Pathway (New)
Homo sapiens
Matched Description: Phenytoin is an anticonvulsant drug used in the prophylaxis and control of various types of … seizures. It can be found under the brand names Dilantin and Phenytek. Although phenytoin first appeared in … is often described as a non-specific sodium channel blocker and targets almost all voltage-gated … inactivation. Sodium channels exist in three main conformations: the resting state, the open state, and … produce voltage-dependent, use-dependent and time-dependent block of sodium-dependent action
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SMP0124452
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Epinephrine B2-Adrenergic Bronchodilation Action Pathway
Homo sapiens
Matched Description: , to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. It is usually … Ca2+, and therefore reduce activation of the MLCK present in the cytosol. These two mechanisms … result in inactivation/reduced activation of MLCK, and as a result, muscle contraction is inhibited and … myosin light chain kinase, muscle relaxation is enhanced. This allows for greater airflow and is
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SMP0130466
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Dopamine Action Pathway
Rattus norvegicus
Matched Description: many heart problems and diseases. Dopamine is a precursor to norepinephrine in the sympathetic … membrane, causing the channels to open and allow Ca2+ into the cell. This causes a high concentration … + binds to troponin to cause cardiac muscle contractions and therefore, an increased heart rate. This … helps conditions like Arrhythmia, myocardial infarctions, open-heart surgery, and trauma-induced … through norepinephrine in noradrenergic neurons outside the brain, and especially in the heart. Low
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