SMP0070359
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Phosphatidylcholine Biosynthesis PC(20:4(8Z,11Z,14Z,17Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
Mus musculus
Matched Proteins: Ethanolaminephosphotransferase 1
Matched Compound Synonyms: 2-amino-1-ethanol … 2-aminoethan-1-ol … 1-eicsoate … 1-eicsoatetraenoyl-2-docosahexaenoyl-sn-glycerol … 1-eicsoic acid
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SMP0666695
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Phospholipid Biosynthesis CL(17:0cycw7/10:0/17:0cycw7/10:0)
Pseudomonas aeruginosa
Matched Description: -phosphate esterified with fatty acids at the sn-1 and sn-2 positions. The reaction starts from a glycerone … dehydrogenase. Sn-glycerol 3-phosphate is transformed to a 1-acyl-sn-glycerol 3-phosphate(1-oleyl-2-lyso … -phosphatidate , 1-palmitoylglycerol 3-phosphate , 1-stearoyl-sn-glycerol 3-phosphate). This can be … achieve by a sn-glycerol-3-phosphate 1-0-acyltransferase that interacts either with a long-chain acyl … -CoA or with an acyl-[acp]. The 1-acyl-sn-glycerol 3-phosphate is transformed into a 1,2-diacyl-sn
Matched Compounds: DG(17:0cycw7/10:0/0:0) … DG(19:1(9Z)/18:1(9Z)/0:0) … CDP-DG(17:0cycw7/10:0) … PS(17:0cycw7/10:0) … PE(17:0cycw7/10:0)
Matched Proteins: Glycerol-3-phosphate 1-O-acyltransferase
Matched Compound Synonyms: 1-heptadec-9-10-cyclo-anoyl-2-decanoyl-sn-glycero-3-phosphoethanolamine … 1-hydroxy-3-(phosphonooxy)acetone … Cdp-diacylglycerol(17:0cycn7/10:0) … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-d-ribofuranosylnicotinamide … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide
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SMP0000704
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Tolmetin Action Pathway
Homo sapiens
Matched Description: action of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H synthase 1 and 2
Matched Proteins: Prostaglandin G/H synthase 1 … Leukotriene-B(4) omega-hydroxylase 1 … Gamma-glutamyltranspeptidase 1 … Glutathione peroxidase 1 … Aldo-keto reductase family 1 member C3
Matched Protein Synonyms: Cyclooxygenase-1 … PGH synthase 1 … PGHS-1 … PHS 1 … Prostaglandin H2 synthase 1
Matched Compound Synonyms: 1-methyl-5-p-toluoylpyrrole-2-acetic acid … 5-(p-toluoyl)-1-methylpyrrole-2-acetic acid … 1-methyl-5-(4-methylbenzoyl)-pyrrole-2-acetate … 1-methyl-5-p-toluoylpyrrole-2-acetate … 5-(p-toluoyl)-1-methylpyrrole-2-acetate
Matched EC Numbers: 1.-.-.-; 1.1.1.357; 1.1.1.112; 1.1.1.188; 1.1.1.239; 1.1.1.64; 1.3.1.20
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SMP0000104
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Indomethacin Action Pathway
Homo sapiens
Matched Description: . Indomethacin can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 … and 2. Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and
Matched Proteins: Prostaglandin G/H synthase 1 … Leukotriene-B(4) omega-hydroxylase 1 … Gamma-glutamyltranspeptidase 1 … Glutathione peroxidase 1 … Aldo-keto reductase family 1 member C3
Matched Protein Synonyms: Cyclooxygenase-1 … PGH synthase 1 … PGHS-1 … PHS 1 … Prostaglandin H2 synthase 1
Matched Compound Synonyms: {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1h-indol-3-yl}acetic acid … 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetate … {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1h-indol-3-yl}acetate … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoic acid
Matched EC Numbers: 1.-.-.-; 1.1.1.357; 1.1.1.112; 1.1.1.188; 1.1.1.239; 1.1.1.64; 1.3.1.20
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SMP0000084
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Etodolac Action Pathway
Homo sapiens
Matched Description: . cyclooxygenase or COX) inhibitors that act on both prostaglandin G/H synthase 1 and 2 (COX-1 and -2 … -1. The first part of this figure depicts the anti-inflammatory, analgesic and antipyretic pathway … derived from fragmentation from megakaryocytes, contain COX-1, but not COX-2. COX-1 activity in … both COX-1 and COX-2. COX-2 in endothelial cells mediates the synthesis of PGI2, an effective … platelet aggregation inhibitor and vasodilator, while COX-1 mediates vasoconstriction and stimulates
Matched Proteins: Leukotriene-B(4) omega-hydroxylase 1 … Gamma-glutamyltranspeptidase 1 … Glutathione peroxidase 1 … Aldo-keto reductase family 1 member C3 … Carbonyl reductase [NADPH] 1
Matched Protein Synonyms: GGT 1 … Gamma-glutamyltransferase 1 … Gamma-glutamyltranspeptidase 1 heavy chain … Gamma-glutamyltranspeptidase 1 light chain … Glutathione hydrolase 1
Matched Compound Synonyms: (1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-acetic acid … 1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid … 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid … 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoic acid
Matched EC Numbers: 1.-.-.-; 1.1.1.357; 1.1.1.112; 1.1.1.188; 1.1.1.239; 1.1.1.64; 1.3.1.20
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SMP0014936
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Phosphatidylcholine Biosynthesis PC(22:5(4Z,7Z,10Z,13Z,16Z)/22:5(7Z,10Z,13Z,16Z,19Z))
Homo sapiens
Matched Proteins: Choline/ethanolaminephosphotransferase 1
Matched Compound Synonyms: 2-amino-1-ethanol … 2-aminoethan-1-ol … 1-docosapentaenoyl-2-docosapentaenoyl-sn-glycerol … 1-osbondoyl-2-docosapentaenoyl-sn-glycerol … Dag(44:10)
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SMP0150453
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Phosphatidylcholine Biosynthesis PC(22:5(7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z))
Bos taurus
Matched Proteins: Cholinephosphotransferase 1
Matched Compound Synonyms: 2-amino-1-ethanol … 2-aminoethan-1-ol … 1-docosapentaenoyl-2-docosapentaenoyl-sn-glycerol … 1-docosapentaenoyl-2-osbondoyl-sn-glycerol … Dag(44:10)
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SMP0000692
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Antipyrine Action Pathway
Homo sapiens
Matched Description: of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H synthase 1 and 2 catalyze
Matched Proteins: Prostaglandin G/H synthase 1 … Leukotriene-B(4) omega-hydroxylase 1 … Gamma-glutamyltranspeptidase 1 … Glutathione peroxidase 1 … Aldo-keto reductase family 1 member C3
Matched Protein Synonyms: Cyclooxygenase-1 … PGH synthase 1 … PGHS-1 … PHS 1 … Prostaglandin H2 synthase 1
Matched Compound Synonyms: 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoate … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoate … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-d-ribofuranosylnicotinamide
Matched EC Numbers: 1.-.-.-; 1.1.1.357; 1.1.1.112; 1.1.1.188; 1.1.1.239; 1.1.1.64; 1.3.1.20
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SMP0014790
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Phosphatidylcholine Biosynthesis PC(20:5(5Z,8Z,11Z,14Z,17Z)/22:5(4Z,7Z,10Z,13Z,16Z))
Homo sapiens
Matched Proteins: Choline/ethanolaminephosphotransferase 1
Matched Compound Synonyms: 2-amino-1-ethanol … 2-aminoethan-1-ol … 1-eicosapentaenoyl-2-docosapentaenoyl-sn-glycerol … 1-eicosapentaenoyl-2-osbondoyl-sn-glycerol … Dag(42:10)
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SMP0014930
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Phosphatidylcholine Biosynthesis PC(22:5(4Z,7Z,10Z,13Z,16Z)/20:5(5Z,8Z,11Z,14Z,17Z))
Homo sapiens
Matched Proteins: Choline/ethanolaminephosphotransferase 1
Matched Compound Synonyms: 2-amino-1-ethanol … 2-aminoethan-1-ol … 1-docosapentaenoyl-2-eicosapentaenoyl-sn-glycerol … 1-osbondoyl-2-eicosapentaenoyl-sn-glycerol … Dag(42:10)
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