SMP0120946
View Pathway
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LPS and Citrate Signaling and Inflammation
Bos taurus
Matched Proteins: Acetyl-CoA carboxylase 1
Matched Compound Synonyms: Adenosine 5'-(trihydrogen pyrophosphate), 5'-5'-ester with 5,10-dihydro-7,8-dimethyl-10-(d-ribo-2,3,4,5-tetrahydroxypentyl)alloxazine … Adenosine 5'-(trihydrogen pyrophosphate), 5'->5'-ester with 5,10-dihydro-7,8-dimethyl-10-(d-ribo-2,3,4,5-tetrahydroxypentyl)alloxazine … Adenosine 5'-{3-[d-ribo-5-(7,8-dimethyl-2,4-dioxo-1,2,3,4,5,10-tetrahydrobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] dihydrogen diphosphate} … Adenosine pyrophosphate 5'-5'-ester with 5,10-dihydro-7,8-dimethyl-10-(d-ribo-2,3,4,5-tetrahydroxypentyl)alloxazine … Adenosine pyrophosphate, 5'-5'-ester with 5,10-dihydro-7,8-dimethyl-10-(d-ribo-2,3,4,5-tetrahydroxypentyl)alloxazine
Immunological
Pathogen-Activated Signaling
Cellular Response
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SMP0011553
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Cardiolipin Biosynthesis CL(16:0/16:0/16:0/24:0)
Saccharomyces cerevisiae
Matched Description: reacts with glycerol-3-phosphate O-acyltransferase resulting in the release of 1-acyl-sn-glycerol 3 … the removal of an acyl chain to form 1-monolysocardiolipin (1-MLCL) via the lipase Cld1p. This is
Matched Proteins: Glycerol-3-phosphate O-acyltransferase 1 … Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase … Lysophosphatidic acid:oleoyl-CoA acyltransferase 1 … Maintenance of mitochondrial morphology protein 1 … Mitochondrial distribution and morphology protein 10
Matched Compound Synonyms: (r)-4-hydroxy-n,n,n-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide inner salt … (r)-4-hydroxy-n,n,n-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide hydroxide inner salt … 1-hydroxy-3-(phosphonooxy)acetone … D-glycerol 1-phosphate … D-glycerol 1-phosphoric acid
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SMP0211315
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Cardiolipin Biosynthesis CL(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/22:5(4Z,7Z,10Z,13Z,16Z)/22:5(4Z,7Z,10Z,13Z,16Z))
Homo sapiens
Matched Description: enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn … -glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). Third, the … enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2
Matched Compounds: LysoPA(16:1(9Z)/0:0) … PA(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … CDP-DG(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … PGP(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … CL(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/22:5(4Z,7Z,10Z,13Z,16Z)/22:5(4Z,7Z,10Z,13Z,16Z))
Matched Proteins: Glycerol-3-phosphate acyltransferase 1, mitochondrial … 1-Acyl-sn-glycerol-3-phosphate acyltransferase epsilon … Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Matched Protein Synonyms: GPAT-1 … 1-AGP acyltransferase 5 … 1-AGPAT 5 … 1-acylglycerol-3-phosphate O-acyltransferase 5 … PGP synthase 1
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0211329
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Cardiolipin Biosynthesis CL(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/22:5(7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z))
Homo sapiens
Matched Description: enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn … -glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). Third, the … enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2
Matched Compounds: LysoPA(16:1(9Z)/0:0) … PA(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … CDP-DG(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … PGP(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … CL(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/22:5(7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z))
Matched Proteins: Glycerol-3-phosphate acyltransferase 1, mitochondrial … 1-Acyl-sn-glycerol-3-phosphate acyltransferase epsilon … Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Matched Protein Synonyms: GPAT-1 … 1-AGP acyltransferase 5 … 1-AGPAT 5 … 1-acylglycerol-3-phosphate O-acyltransferase 5 … PGP synthase 1
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0211341
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Cardiolipin Biosynthesis CL(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:4(5Z,8Z,11Z,14Z))
Homo sapiens
Matched Description: enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn … -glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). Third, the … enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2
Matched Compounds: LysoPA(16:1(9Z)/0:0) … PA(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … CDP-DG(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … PGP(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … CL(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:4(5Z,8Z,11Z,14Z))
Matched Proteins: Glycerol-3-phosphate acyltransferase 1, mitochondrial … 1-Acyl-sn-glycerol-3-phosphate acyltransferase epsilon … Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Matched Protein Synonyms: GPAT-1 … 1-AGP acyltransferase 5 … 1-AGPAT 5 … 1-acylglycerol-3-phosphate O-acyltransferase 5 … PGP synthase 1
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0642331
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Cardiolipin Biosynthesis CL(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/20:4(5Z,8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
Rattus norvegicus
Matched Description: enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn … -glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). Third, the … enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2
Matched Compounds: LysoPA(16:1(9Z)/0:0) … PA(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … CDP-DG(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … PGP(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … CL(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/20:4(5Z,8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
Matched Proteins: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0642363
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Cardiolipin Biosynthesis CL(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/22:5(4Z,7Z,10Z,13Z,16Z)/22:5(7Z,10Z,13Z,16Z,19Z))
Rattus norvegicus
Matched Description: enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn … -glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). Third, the … enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2
Matched Compounds: LysoPA(16:1(9Z)/0:0) … PA(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … CDP-DG(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … PGP(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … CL(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/22:5(4Z,7Z,10Z,13Z,16Z)/22:5(7Z,10Z,13Z,16Z,19Z))
Matched Proteins: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0642382
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Cardiolipin Biosynthesis CL(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/22:5(7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z))
Rattus norvegicus
Matched Description: enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn … -glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). Third, the … enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2
Matched Compounds: LysoPA(16:1(9Z)/0:0) … PA(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … CDP-DG(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … PGP(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)) … CL(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/22:5(7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z))
Matched Proteins: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0024728
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De Novo Triacylglycerol Biosynthesis TG(20:4(5Z,8Z,11Z,14Z)/14:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
Homo sapiens
Matched Description: acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn … endoplasmic reticulum membrane. The enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into
Matched Proteins: Glycerol-3-phosphate acyltransferase 1, mitochondrial … 1-Acyl-sn-glycerol-3-phosphate acyltransferase alpha … Diacylglycerol O-acyltransferase 1
Matched Protein Synonyms: GPAT-1 … 1-AGP acyltransferase 1 … 1-AGPAT 1 … 1-acylglycerol-3-phosphate O-acyltransferase 1 … Lipin-1
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0024836
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De Novo Triacylglycerol Biosynthesis TG(20:4(5Z,8Z,11Z,14Z)/20:3(5Z,8Z,11Z)/18:3(9Z,12Z,15Z))
Homo sapiens
Matched Description: acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn … endoplasmic reticulum membrane. The enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into
Matched Proteins: Glycerol-3-phosphate acyltransferase 1, mitochondrial … 1-Acyl-sn-glycerol-3-phosphate acyltransferase alpha … Diacylglycerol O-acyltransferase 1
Matched Protein Synonyms: GPAT-1 … 1-AGP acyltransferase 1 … 1-AGPAT 1 … 1-acylglycerol-3-phosphate O-acyltransferase 1 … Lipin-1
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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