SMP0125100
View Pathway
|
Itraconazole Metabolism
Homo sapiens
Matched Description: intestine into the intestinal epithelial cell possibly via solute carrier family 15 member 1, one of 3
Matched Proteins: Solute carrier family 15 member 1
Matched Protein Synonyms: Peptide transporter 1
Matched Compound Synonyms: 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-d-ribofuranosylnicotinamide … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-d-ribofuranosyl-3-pyridinecarboxamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosyl-3-pyridinecarboxamide … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-d-ribofuranosylnicotinamide
|
SMP0130457
View Pathway
|
Amine Oxidase Serotonin
Mus musculus
Matched Proteins: Tryptophan 5-hydroxylase 1 … Voltage-dependent L-type calcium channel subunit beta-1
Matched Protein Synonyms: Calcium channel voltage-dependent subunit beta 1
Matched Compound Synonyms: 1-beta-3-indolylalanine
|
SMP0130947
View Pathway
|
Norepinephrine Neurological
Mus musculus
Matched Protein Synonyms: Calcium channel, L type, alpha-1 polypeptide isoform 5
Matched Compound Synonyms: (r)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol … 4-[(1r)-2-amino-1-hydroxyethyl]-1,2-benzenediol … 4-(2-amino-1-hydroxyethyl)-1,2-benzenediol … L-2-amino-1-(3,4-dihydroxyphenyl)ethanol … 1-dehydroascorbate
|
SMP0063814
View Pathway
|
Complement Pathway
Homo sapiens
Matched Description: two pathways.
In the lectin pathway, mannan-binding lectin serine proteases (MASP) 1 and 2, as well … salmonella and listeria, as well as some viruses, including HIV-1, and fungal pathogens, such as
Matched Proteins: Mannan-binding lectin serine protease 1
Matched Protein Synonyms: Complement component 1 subcomponent r
Immunological
Kinase Signaling
Pathogen-Activated Signaling
Cellular Response
|
SMP0125985
View Pathway
|
Maraviroc Action Pathway
Homo sapiens
Matched Description: used to treat HIV-1 infections. It was developed by the drug company Pfizer.
Maraviroc blocks HIV … membrane of CD4 cells (T cells). This prevents the interaction of HIV-1 gp120 and CCR5 which is necessary for HIV to enter the cell and replicate.
Matched Proteins: HIV-1 protease
Matched Genes: HIV-1 protease
Matched Protein Synonyms: HIV-1 fusion coreceptor
|
SMP0126267
View Pathway
|
Esketamine Action Pathway
Homo sapiens
Matched Proteins: Glutamate [NMDA] receptor subunit epsilon-1 … Glutamate [NMDA] receptor subunit zeta-1
Matched Protein Synonyms: Calcium channel, L type, alpha-1 polypeptide isoform 4
Matched Compound Synonyms: 1-amino-propane-1,3-dicarboxylate … 1-amino-propane-1,3-dicarboxylic acid … 1-aminopropane-1,3-dicarboxylate … 1-aminopropane-1,3-dicarboxylic acid … 1-amino-propane-1,3-dicarboxylate
|
SMP0126453
View Pathway
|
Ethanol NMDA Antagonist Action Pathway
Homo sapiens
Matched Proteins: Glutamate [NMDA] receptor subunit epsilon-1 … Glutamate [NMDA] receptor subunit zeta-1
Matched Protein Synonyms: Calcium channel, L type, alpha-1 polypeptide isoform 4
Matched Compound Synonyms: 1-amino-propane-1,3-dicarboxylate … 1-amino-propane-1,3-dicarboxylic acid … 1-aminopropane-1,3-dicarboxylate … 1-aminopropane-1,3-dicarboxylic acid … 1-amino-propane-1,3-dicarboxylate
|
SMP0126469
View Pathway
|
Orphenadrine NMDA Antagonist Action Pathway
Homo sapiens
Matched Proteins: Glutamate [NMDA] receptor subunit epsilon-1 … Glutamate [NMDA] receptor subunit zeta-1
Matched Protein Synonyms: Calcium channel, L type, alpha-1 polypeptide isoform 4
Matched Compound Synonyms: 1-amino-propane-1,3-dicarboxylate … 1-amino-propane-1,3-dicarboxylic acid … 1-aminopropane-1,3-dicarboxylate … 1-aminopropane-1,3-dicarboxylic acid … 1-amino-propane-1,3-dicarboxylate
|
SMP0126495
View Pathway
|
Clofarabine Action Pathway
Homo sapiens
Matched Proteins: Equilibrative nucleoside transporter 1
Matched Protein Synonyms: Solute carrier family 29 member 1
|
SMP0175202
View Pathway
|
Latanoprostene bunod Action Pathway
Homo sapiens
Matched Proteins: Carbonic anhydrase 1 … Adenylate cyclase type 10 … Potassium-transporting ATPase alpha chain 1
Matched Protein Synonyms: Tissue-specific extinguisher 1
Matched Compound Synonyms: Hydrocarbonate(1-) … Potassium ion(1+) … Potassium(1+) ion … Potassium(1+) … Potassium ion(1+)
|