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Matched Description: carbon and energy source. Toluene enters the bacterial cell by passive diffusion due to its hydrophobic … . Subsequently, Benzylsuccinyl-CoA undergoes a series of enzymatic reactions to form Benzoylsuccinyl-CoA, and … finally benzoyl-CoA, which enters the benzoate degradation pathway, providing the bacteria with energy and carbon for growth and survival.

Matched Proteins: Peptidase propeptide and YPEB domain protein

Matched Description: compound can also be present in E.coli through the interaction of D-fructose and a mannose PTS permease … be present in E.coli through the interaction of Alpha-D-mannose and a mannose PTS permease which … hydrogen ion and gtp undergoes a reaction with a mannose-1-phosphate guanylyltransferase, releasing a … pyrophosphate and producing a guanosine diphosphate mannose. Guanosine diphosphate mannose interacts … with gdp-mannose 4,6-dehydratase releasing a water, and gdp-4-dehydro-6-deoxy-D-mannose. This compound

Matched Proteins: PTS system, N-acetylgalactosamine-and galactosamine-specific IIA component … PTS system, maltose and glucose-specific IIC component

Matched Description: Ruxolitinib is a medication used to manage and treat myelofibrosis, polycythemia vera, and steroid … . Ruxolitinib is a selective and potent inhibitor of JAK2 and JAK1, with some affinity against JAK3 … and TYK2. Anticancer effects of ruxolitinib are attributed to its inhibition of JAKs and JAK … myeloproliferation and suppresses the plasma levels of pro-inflammatory cytokines such as IL-6 and TNF-α … cells and heightened production of pro-inflammatory cytokines. By blocking JAK1 and JAk2, ruxolitinib

Matched Proteins: Signal transducer and activator of transcription 5A … Signal transducer and activator of transcription 3

Matched Description: -receptor interactions in the endosome (stimulation) and modifications of the primary or quaternary structure of the receptor (activation).

Matched Proteins: Signal transducer and activator of transcription 3 … Signal transducer and activator of transcription 5A

Matched Description: an ATP hydrolysis and dehydrogenation reaction by the adenylyl-sulfate kinase. Phoaphoadenosine … phosphosulfate is finally dehydrogenated and converted to sulfite by phosphoadenosine phosphosulfate … reductase. This reaction requires magnesium, and adenosine 3',5'-diphosphate is the bi-product. A … conversion of sulfite to hydrogen sulfide through hygrogenation and the deoxygenation of sulfite to form a … water molecule. The reaction is catalyzed by the sulfite reductase [NADPH] flavoprotein alpha and

Matched Proteins: Sulfate and thiosulfate binding protein CysP … Sulfate and thiosulfate import ATP-binding protein CysA

Matched Description: an ATP hydrolysis and dehydrogenation reaction by the adenylyl-sulfate kinase. Phoaphoadenosine … phosphosulfate is finally dehydrogenated and converted to sulfite by phosphoadenosine phosphosulfate … reductase. This reaction requires magnesium, and adenosine 3',5'-diphosphate is the bi-product. A … conversion of sulfite to hydrogen sulfide through hygrogenation and the deoxygenation of sulfite to form a … water molecule. The reaction is catalyzed by the sulfite reductase [NADPH] flavoprotein alpha and

Matched Proteins: Sulfate and thiosulfate binding protein CysP … Sulfate and thiosulfate import ATP-binding protein CysA

Matched Description: an ATP hydrolysis and dehydrogenation reaction by the adenylyl-sulfate kinase. Phoaphoadenosine … phosphosulfate is finally dehydrogenated and converted to sulfite by phosphoadenosine phosphosulfate … reductase. This reaction requires magnesium, and adenosine 3',5'-diphosphate is the bi-product. A … conversion of sulfite to hydrogen sulfide through hygrogenation and the deoxygenation of sulfite to form a … water molecule. The reaction is catalyzed by the sulfite reductase [NADPH] flavoprotein alpha and

Matched Proteins: Sulfate and thiosulfate binding protein CysP … Sulfate and thiosulfate import ATP-binding protein CysA

Matched Description: an ATP hydrolysis and dehydrogenation reaction by the adenylyl-sulfate kinase. Phoaphoadenosine … phosphosulfate is finally dehydrogenated and converted to sulfite by phosphoadenosine phosphosulfate … reductase. This reaction requires magnesium, and adenosine 3',5'-diphosphate is the bi-product. A … conversion of sulfite to hydrogen sulfide through hygrogenation and the deoxygenation of sulfite to form a … water molecule. The reaction is catalyzed by the sulfite reductase [NADPH] flavoprotein alpha and

Matched Proteins: Sulfate and thiosulfate binding protein CysP … Sulfate and thiosulfate import ATP-binding protein CysA

Matched Description: isochorismate synthase. Isochorismate then interacts with 2-oxoglutare and a hydrogen ion through a 2 … carbon dioxide and a 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate. The latter … resulting in the release of a pyruvate and a (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate … water molecule and a 2-succinylbenzoate. This compound then interacts with a coenzyme A and an ATP … through a o-succinylbenzoate CoA ligase resulting in the release of a diphosphate, a AMP and a

Matched Proteins: AMP-dependent synthetase and ligase

Matched Description: ,octacis-undecaprenol and a Uridine 5'-monophosphate. The N-acetyl-α-D-glucosaminyl-diphospho-ditrans … ,octacis-undecaprenol then reacts with an UDP-ManNAcA from the Amino sugar and nucleotide sugar … resulting in a uridine 5' diphosphate, a hydrogen ion and a Undecaprenyl N-acetyl-glucosaminyl-N-acetyl … metabolize by interacting with a hydrogen ion and a thymidine 5-triphosphate by either reacting with a … pyrophosphate and a dTDP-D-glucose. The latter compound is then dehydrated through an dTDP-glucose 4,6

Matched Proteins: Membrane protein involved in the export of O-antigen and teichoic acid