SMP0062621
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Tolpropamine H1-Antihistamine Action
Homo sapiens
Matched Description: of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to … treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. Reducing the … activity of the NF-κB immune response transcription factor through the phospholipase C and the … phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the expression of … pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors. Furthermore, lowering
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SMP0062886
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Pimethixene H1-Antihistamine Action
Homo sapiens
Matched Description: of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to … treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. Reducing the … activity of the NF-κB immune response transcription factor through the phospholipase C and the … phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the expression of … pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors. Furthermore, lowering
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SMP0175127
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Olopatadine H1-Antihistamine Immune Response Action Pathway
Homo sapiens
Matched Description: Olopatadine is a histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis. H1 … -antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered … conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit the immune … response, in blood vessels to constrict dilated blood vessels, and in smooth muscles of lungs and … at the H1 receptor and are administered to attenuate inflammatory process in order to treat
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SMP0126403
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Anisotropine Methylbromide M2 GI Tract Relaxation Action Pathway
Homo sapiens
Matched Description: methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the … tone of the ureter and urinary bladder and may have a slight relaxant action on the bile ducts and … gallbladder. In general, smaller doses of anisotropine methylbromide inhibit salivary and bronchial … secretions, sweating, and accommodation; cause dilatation of the pupil; and increase the heart rate … . Larger doses are required to decrease motility of the gastrointestinal and urinary tracts and to
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SMP0126402
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Hyoscyamine M2 Smooth Muscle Relaxation Action Pathway
Homo sapiens
Matched Description: and renal colic, and acute rhinitis. It can be found under the brand names Anaspaz, Donnatal, Ed … Reformulated Oct 2013, Urin DS, Urogesic Blue Reformulated Apr 2012, Ustell, and Utira. Intravenous … hysocyamine has been used to reduce gastric motility, reduce pancreatic pain and secretions, to … of partial heart block, improve visualization of the kidneys, and for symptomatic relief of biliary … and renal colic. Intravenous hyoscyamine is also used pre-operatively to reduce secretions of the
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SMP0175094
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Mepyramine H1-Antihistamine Immune Response Action Pathway
Homo sapiens
Matched Description: , hypersensitivity reactions, and pruritic skin disorders. H1-antihistamines interfere with the agonist action of … histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act … blood vessels, and in smooth muscles of lungs and intestines to relax those muscles.
H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate
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SMP0175099
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Acrivastine H1-Antihistamine Immune Response Action Pathway
Homo sapiens
Matched Description: such as sneezing, rhinorrhea, pruritus, lacrimation, and nasal congestion. H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … vessels to constrict dilated blood vessels, and in smooth muscles of lungs and intestines to relax … and are administered to attenuate inflammatory process in order to treat conditions such as allergic
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SMP0175106
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Diphenylpyraline H1-Antihistamine Immune Response Action Pathway
Homo sapiens
Matched Description: Diphenylpyraline is an antihistamine used for the treatment of allergic rhinitis, hay fever, and … receptor and are administered to attenuate inflammatory process in order to treat conditions such as … allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors in T … -cells to inhibit the immune response, in blood vessels to constrict dilated blood vessels, and in … smooth muscles of lungs and intestines to relax those muscles.
H1-antihistamines interfere with the
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SMP0175117
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Rupatadine H1-Antihistamine Immune Response Action Pathway
Homo sapiens
Matched Description: Rupatadine is a selective histamine H1 receptor antagonist and platelet activating factor (PAF … histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on … vessels, and in smooth muscles of lungs and intestines to relax those muscles.
H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate
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SMP0411147
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Lipopolysaccharide Biosynthesis
Escherichia coli SE15
Matched Description: either the fructose 6-phosphate produced by glycolysis and pyruvate dehydrogenase or obtained from the … and a glucosamine 6-phosphate. The latter compound is isomerized through a phosphoglucosamine mutase … through a bifunctional protein glmU resulting in a Coenzyme A, hydrogen ion and N-acetyl-glucosamine 1 … -phosphate. The latter interacts with UTP and hydrogen ion through the bifunctional protein glmU … resulting in a pyrophosphate and a UDP-N-acetylglucosamine. UDP-N-acetylglucosamine iinteracts with (3R)-3
Matched Proteins: outer membrane lipopolysaccharide transport and assembly complex - LptE subunit … outer membrane lipopolysaccharide transport and assembly complex - LptD subunit
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