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Matched Description: pathway of choline biosynthesis. First, serine decarboxylase (SDC) uses a proton and a pyridoxal 5 … that this is only the probable ethanolamine kinase in Arabidopsis thaliana and requires further … research to confirm its function. Steps 3, 4, and 5 are catalyzed by phosphoethanolamine N … phosphocholine and utilize S-adenosyl-L-methionine as a methyl donor. The intermediates are as follows: O … -Phosphoethanolamine, N-methylethanolamine phosphate, and N-dimethylethanolamine phosphate. Sixth

Matched Description: The TOR signalling pathway is responsible for the cellular reactions towards nutrient and energy … availability and hypoxia/stress. When TOR1/2 is activated, it activates TAP42 which in turn can … -Gln3 complex and the separation of Ure2 and Gln3. Gln3 then gets incorporated into the nucleus

Matched Description: lesions with disrupted blood-brain barrier and/or abnormal vascularity in the brain, spine, and associated … tissues in adult and pediatric patients, including term neonates. It is also indicated for … visualization of lesions in the head and neck in adult patients. Gadoteridol provides contrast enhancement … of the brain, spine and surrounding tissues resulting in improved visualization (compared with … head, neck, liver, breast, musculoskeletal system and soft tissue pathologies. n MRI, visualization

Matched Description: Globoid Cell Leukodistrophy (GLD), also called Krabbe disease and galactosylceramide lipidosis, is … population and a worldwide incidence of 1/100,000-1/250,000 live births. GLD is an autosomal recessive … is a lysosomal protein that hydrolyzes the galactose ester bonds of ceramides and ceramide … derivatives including galactocerebroside, galactosylsphingosine (psychosine), lactosylceramide, and … catabolism (via the removal of galactose) of galactosylceramide, a major lipid in myelin, kidney, and

Matched Description: aminoglycosides family and it is derived from Streptomyces griseus which was the first effective … development of resistance and toxicity. Streptomycin goes through 3 phases in order to infiltrate the … bacterial cell and inhibit protein synthesis: the first phase is the binding of polycationic drug to the … travels and binds to the 16rRNA and 30S ribosomal subunit. The final phase is the inhibition of protein … synthesis and the accumulation of Streptomycin in the cell which further exacerbates its inhibition

Matched Description: including sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias … neuron back to resting potential. The action potentials created travel down the axon of the neuron and … causes synaptic vesicles containing neurotransmitters like glutamate to fuse with the membrane and expel … the neurotransmitter into the synapse. Glutamate binds to AMPA and NMDA receptor on the post … , flecainide prevents the depolarization phase, inhibiting action potential generation and the

Matched Description: Atoltivimab (REGN 3470), Odesivimab (REGN 3471), and Maftivimab are monoclonal antibody (mAb) and … and GP2 glycoprotein of Zaire ebolavirus. INMAZEB, formally known as REGN-EB3, is a combination of … Atoltivimab, Odesivimab, and Maftivimab in equimolar proportions. Each of them bind to a distinct … portion of the GP1,2 glycoprotein and protect against ebola virus infection.It has not been established … produced by Regeneron Pharmaceuticals and was granted FDA approval on October 14, 2020. Ebola virus (Zaire

Matched Description: hydrogen bonding. This binding ends up causing crosslinks and strand breaks. Mitoxantrone can also … interferes with ribonucleic acid (RNA) and is a potent inhibitor of topoisomerase II, the enzyme … responsible for uncoiling and repairing damaged DNA. This drug has a cytocidal effect on proliferating cells … and nonproliferation cells, this suggests that it is not a cell cycle-specific drug. Mitoxantrone is administered in an intravenous injection.

Matched Description: Globoid Cell Leukodistrophy (GLD), also called Krabbe disease and galactosylceramide lipidosis, is … population and a worldwide incidence of 1/100,000-1/250,000 live births. GLD is an autosomal recessive … is a lysosomal protein that hydrolyzes the galactose ester bonds of ceramides and ceramide … derivatives including galactocerebroside, galactosylsphingosine (psychosine), lactosylceramide, and … catabolism (via the removal of galactose) of galactosylceramide, a major lipid in myelin, kidney, and

Matched Description: hydrogen ion, a water molecule and a (2z)-2-aminobut-2-enoate. The latter compound then isomerizes … to a 2-iminobutanoate, This compound then reacts spontaneously with hydrogen ion and a water … molecule resulting in a ammonium and a 2-Ketobutyric acid. The latter compound interacts with CoA through a … pyruvate formate-lyase / 2-ketobutyrate formate-lyase resulting in a formic acid and a propionyl … phosphate. Propionyl-CoA interacts with oxalacetic acid and a water molecule through a 2-methylcitrate