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Matched Description: dividing cells. Microtubules are made up of α- and β- tubulin heterodimers arranged head … to tail and assembled to form a cylinder. Microtubules possess complex polymerization dynamics that … are essential for movement of chromosomes and proper segregation of daughter cells during mitosis … one to one ratio and stimulate microtubule polymerization. At lower clinically relevant drug … concentrations, docetaxel stabilizes microtubules and prohibits further polymerization and depolymerization

Matched Description: of hydromorphone will eventually lead to reduced pain because of decreased nerve conduction and … and activation of potassium channels via facilitated by G-protein.

Matched Description: cyclase, reducing the level of intracellular cAMP. G(i) also activates potassium channels and … conduction and reduced neurotransmitter release, which blocks the perception of pain signals.

Matched Description: blocking β1-adrenergic receptors within the myocardium and β2-adrenergic receptors within bronchial and

Matched Description: eventually lead to reduced pain because of decreased nerve conduction and release of neurotransmitter … . Hyperpolarization of neuron is caused by inactivation of calcium channels and activation of potassium channels via facilitated by G-protein.

Matched Description: acetate will eventually lead to reduced pain because of decreased nerve conduction and release of … neurotransmitter. Hyperpolarization of neuron is caused by inactivation of calcium channels and

Matched Description: Nalbuphine (also known as Rubuphine and Nubain) is a competitive antagonist of mu-type and kappa

Matched Description: phosphoenolpyruvate (PEP) and D-erythrose 4-phosphate (E4P) are converted to chorismate, the common … precursor of the aromatic amino acids phenylalanine, tyrosine, and tryptophan as well as other metabolites … agents, anti-parasitic agents, and herbicides. PEP can enter this pathway either from plastidic … simultaneously. Firstly, DAHP synthase, with the help of reduced thioredoxin (TRX) and a divalent … cation (e.g. manganese) as cofactors, converts PEP, E4P, and water to 3-deoxy-D-arabino-heptulosonic

Matched Description: Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines … . It is also useful in treating irritable bowel syndrome (IBS) and similar conditions. Alverine also

Matched Description: especially effective against Candida albicans (more effective than amphotericin B), and is … irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.