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Matched Description: , and a norepinephrine reuptake inhibtor. It is an agonist of mu, kappa, and delta opioid receptors. It … for GDP on the G-protein complex. As the effector system is adenylate cyclase and cAMP located at … . Opioids close N-type voltage-operated calcium channels and open calcium-dependent inwardly rectifying … potassium channels. This results in hyperpolarization and reduced neuronal excitability. Morphine acts … at A delta and C pain fibres in the dorsal horn of the spinal cord. By decreasing neurotransmitter

Matched Description: molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli … to bind to and hydrolyze guanosine triphosphate (GTP) to guanosine diphosphate (GDP). When they are … bound to GTP, they are 'on', and, when they are bound to GDP, they are 'off'. G proteins belong to … to a domain of the GPCR located outside the cell, and an intracellular GPCR domain then in turn … protein-coupled receptors and G proteins working together transmit signals from many hormones

Matched Description: Framycetin is an antibiotic from the aminoglycosides family. It is used in various formulations and … combinations with other agents to treat hemorrhoids, eye and ear infections, and to reduce nasal … bacterium unable to synthesize proteins. It binds to specific 30S-subunit proteins and 16S rRNA, four … nucleotides of 16S rRNA, and a single amino acid of protein S12. This interferes with the decoding site … base in the anticodon. This leads to interference with the initiation complex, and misreading of

Matched Description: name Plendil. Felodipine decreases arterial smooth muscle contractility and subsequent … reversibly competes against nitrendipine and other DHP CCBs for DHP binding sites in vascular smooth … muscle and cultured rabbit atrial cells. Calcium ions entering the cell through these channels bind to … calmodulin. Calcium-bound calmodulin then binds to and activates myosin light chain kinase (MLCK … decreases the contractile activity of arterial smooth muscle cells and results in vasodilation. The

Matched Description: reacts with water through a GTP cyclohydrolase resulting in the release of formic acid, pyrophosphate and … resulting in the release of NAD and 2,5-Diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate. The … synthase resulting in the release of formic acid and 1-Deoxy-L-glycero-tetrulose 4-phosphate. The latter … riboflavin synthase resulting in the release of 5-Amino-6-ribitylamino uracil and Riboflavin. The … Riboflavin reacts with an ATP driven riboflavin synthase resulting in the release of ADP and Flavin

Matched Description: as a carbon source and involves the conversion of benzoate into intermediates that can enter the … is activated by the benM gene which encodes for a transcriptional regulator and is outside of this … regulator, enhancing its ability to bind the promoter and facilitate RNA polymerase recruitment, thus … the catechil ortho-cleavage pathway and eventually feeds the TCA cycle. benB encodes benzoate 1,2 … operon is influenced by benK and benP which are also outside of the operon and encode for membrane

Matched Description: as a carbon source and involves the conversion of benzoate into intermediates that can enter the … is activated by the benM gene which encodes for a transcriptional regulator and is outside of this … regulator, enhancing its ability to bind the promoter and facilitate RNA polymerase recruitment, thus … the catechil ortho-cleavage pathway and eventually feeds the TCA cycle. benB encodes benzoate 1,2 … operon is influenced by benK and benP which are also outside of the operon and encode for membrane

Matched Description: as a carbon source and involves the conversion of benzoate into intermediates that can enter the … is activated by the benM gene which encodes for a transcriptional regulator and is outside of this … regulator, enhancing its ability to bind the promoter and facilitate RNA polymerase recruitment, thus … the catechil ortho-cleavage pathway and eventually feeds the TCA cycle. benB encodes benzoate 1,2 … operon is influenced by benK and benP which are also outside of the operon and encode for membrane

Matched Description: as a carbon source and involves the conversion of benzoate into intermediates that can enter the … is activated by the benM gene which encodes for a transcriptional regulator and is outside of this … regulator, enhancing its ability to bind the promoter and facilitate RNA polymerase recruitment, thus … the catechil ortho-cleavage pathway and eventually feeds the TCA cycle. benB encodes benzoate 1,2 … operon is influenced by benK and benP which are also outside of the operon and encode for membrane

Matched Description: as a carbon source and involves the conversion of benzoate into intermediates that can enter the … is activated by the benM gene which encodes for a transcriptional regulator and is outside of this … regulator, enhancing its ability to bind the promoter and facilitate RNA polymerase recruitment, thus … the catechil ortho-cleavage pathway and eventually feeds the TCA cycle. benB encodes benzoate 1,2 … operon is influenced by benK and benP which are also outside of the operon and encode for membrane