SMP0125672
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3-Methylglutaconic Aciduria Type IV
Homo sapiens
Matched Compounds: 3-Methyl-1-hydroxybutyl-ThPP … 2-Methyl-1-hydroxypropyl-ThPP
Matched Proteins: Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
Matched Protein Synonyms: Enoyl-CoA hydratase 1 … 3-methylcrotonyl-CoA carboxylase 1 … Enoyl-CoA hydratase 1 … Enoyl-CoA hydratase 1 … Enoyl-CoA hydratase 1
Matched Compound Synonyms: Thiamine(1+) diphosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate … 3-carbamoyl-1-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate
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SMP0000065
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Ubiquinone Biosynthesis
Homo sapiens
Matched Description: chemical group, and 10 refers to the isoprenyl chemical subunits. Ubiquinone is a carrier of hydrogen
Matched Protein Synonyms: 3-demethylubiquinone-10 3-methyltransferase … Timing protein clk-1 homolog … 3-demethylubiquinone-10 3-methyltransferase
Matched Compound Synonyms: (2e,6e,10e,14e,18e)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl trihydrogen diphosphate … (2e,6e,10e,14e,18e)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl trihydrogen diphosphoric acid … [1-(adenin-9-yl)-1,5-dideoxy-beta-d-ribofuranos-5-yl][(3s)-3-amino-3-carboxypropyl](methyl)sulfonium … S-[1-(adenin-9-yl)-1,5-dideoxy-beta-d-ribofuranos-5-yl]-l-homocysteine … 2-[(2e,6e,10e,14e,18e)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl]-6-methoxy-1,4-benzoquinone
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SMP0000327
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Phenytoin (Antiarrhythmic) Action Pathway
Homo sapiens
Matched Proteins: Beta-1-syntrophin … Alpha-1-syntrophin … Epoxide hydrolase 1 … Stromal cell-derived factor 2-like protein 1 … UDP-glucuronosyltransferase 1-1
Matched Protein Synonyms: 59 kDa dystrophin-associated protein A1 acidic component 1 … Pro-TGF-alpha cytoplasmic domain-interacting protein 1 … Syntrophin-1 … Cytochrome P450 PB-1 … Cytochrome P450 PB-1
Matched Compound Synonyms: 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-d-ribofuranosyl-3-pyridinecarboxamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosyl-3-pyridinecarboxamide … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-d-ribofuranosylnicotinamide … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide
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SMP0000330
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Tocainide Action Pathway
Homo sapiens
Matched Proteins: Beta-1-syntrophin … Alpha-1-syntrophin … Sodium/potassium-transporting ATPase subunit alpha-1 … Sodium/potassium-transporting ATPase subunit beta-1 … G protein-activated inward rectifier potassium channel 1
Matched Protein Synonyms: 59 kDa dystrophin-associated protein A1 acidic component 1 … Pro-TGF-alpha cytoplasmic domain-interacting protein 1 … Syntrophin-1 … Na(+)/K(+) ATPase alpha-1 subunit … Sodium pump subunit alpha-1
Matched Compound Synonyms: Potassium(1+) ion … Potassium(1+) … Potassium ion(1+) … Potassium(1+) ion … Potassium(1+)
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SMP0000375
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Verapamil Action Pathway
Homo sapiens
Matched Proteins: Voltage-dependent L-type calcium channel subunit beta-1 … Sodium/potassium-transporting ATPase subunit alpha-1 … Sodium/potassium-transporting ATPase subunit beta-1 … G protein-activated inward rectifier potassium channel 1 … Disks large homolog 1
Matched Protein Synonyms: Calcium channel voltage-dependent subunit beta 1 … Na(+)/K(+) ATPase alpha-1 subunit … Sodium pump subunit alpha-1 … Sodium/potassium-dependent ATPase subunit beta-1 … IRK-1
Matched Compound Synonyms: Potassium(1+) ion … Potassium(1+) … Potassium ion(1+) … Potassium(1+) ion … Potassium(1+)
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SMP0000380
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Nimodipine Action Pathway
Homo sapiens
Matched Proteins: Voltage-dependent L-type calcium channel subunit beta-1 … Sodium/potassium-transporting ATPase subunit alpha-1 … Sodium/potassium-transporting ATPase subunit beta-1 … G protein-activated inward rectifier potassium channel 1 … Disks large homolog 1
Matched Protein Synonyms: Calcium channel voltage-dependent subunit beta 1 … Na(+)/K(+) ATPase alpha-1 subunit … Sodium pump subunit alpha-1 … Sodium/potassium-dependent ATPase subunit beta-1 … IRK-1
Matched Compound Synonyms: Potassium(1+) ion … Potassium(1+) … Potassium ion(1+) … Potassium(1+) ion … Potassium(1+)
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SMP0000659
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Timolol Action Pathway
Homo sapiens
Matched Description: like propranolol or oxprenolol, begins its journey by inhibiting the beta-1 adrenergic receptors in … -dependent protein kinase type 1-alpha regulatory subunit. From there, cAMP-dependent protein … ,14Z)) catalyzing into DG(14:0/14:1(9Z)/0:0) and inositol 1,4,5-triphosphate with the help of the … enzyme 1-phosphatidylinositol 4,5-biphosphate phosphodiesterase beta-1. This enzyme is activated through … the G-protein signalling cascade, which stems from the type-1 angiotensin II receptor. Around the
Matched Proteins: Beta-1 adrenergic receptor … Sodium/potassium-transporting ATPase subunit alpha-1 … Sodium/potassium-transporting ATPase subunit beta-1 … G protein-activated inward rectifier potassium channel 1 … Disks large homolog 1
Matched Protein Synonyms: Beta-1 adrenoreceptor … Na(+)/K(+) ATPase alpha-1 subunit … Sodium pump subunit alpha-1 … Sodium/potassium-dependent ATPase subunit beta-1 … IRK-1
Matched Compound Synonyms: Potassium(1+) ion … Potassium(1+) … Potassium ion(1+) … Potassium(1+) ion … Potassium(1+)
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SMP0000666
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Levobunolol Action Pathway
Homo sapiens
Matched Proteins: Beta-1 adrenergic receptor … Sodium/potassium-transporting ATPase subunit alpha-1 … Sodium/potassium-transporting ATPase subunit beta-1 … G protein-activated inward rectifier potassium channel 1 … Disks large homolog 1
Matched Protein Synonyms: Beta-1 adrenoreceptor … Na(+)/K(+) ATPase alpha-1 subunit … Sodium pump subunit alpha-1 … Sodium/potassium-dependent ATPase subunit beta-1 … IRK-1
Matched Compound Synonyms: Potassium ion(1+) … Potassium(1+) ion … Potassium(1+) … Potassium ion(1+) … Potassium(1+) ion
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SMP0000296
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Acebutolol Action Pathway
Homo sapiens
Matched Description: Acebutolol (also known as Sectral or Prent) is a selective β1 adrenergic receptor antagonist … (ISA) with effective range of dosage. Adrenaline (also known as epinephrine) can activate β1
Matched Proteins: Beta-1 adrenergic receptor … Sodium/potassium-transporting ATPase subunit alpha-1 … Sodium/potassium-transporting ATPase subunit beta-1 … G protein-activated inward rectifier potassium channel 1 … Disks large homolog 1
Matched Protein Synonyms: Beta-1 adrenoreceptor … Na(+)/K(+) ATPase alpha-1 subunit … Sodium pump subunit alpha-1 … Sodium/potassium-dependent ATPase subunit beta-1 … IRK-1
Matched Compound Synonyms: Potassium ion(1+) … Potassium(1+) ion … Potassium(1+) … Potassium ion(1+) … Potassium(1+) ion
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SMP0000301
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Esmolol Action Pathway
Homo sapiens
Matched Description: Esmolol, sold as Brevibloc, is a cardioselective beta-1 receptor blocker drug. As a beta-blocker … injected intravenously, and when it enters the heart, it binds to the beta-1 adrenergic receptor … , preventing signalling. Normally, epinephrine and norepinephrine bind to the beta-1 adrenergic receptor
Matched Proteins: Beta-1 adrenergic receptor … Sodium/potassium-transporting ATPase subunit alpha-1 … Sodium/potassium-transporting ATPase subunit beta-1 … G protein-activated inward rectifier potassium channel 1 … Disks large homolog 1
Matched Protein Synonyms: Beta-1 adrenoreceptor … Na(+)/K(+) ATPase alpha-1 subunit … Sodium pump subunit alpha-1 … Sodium/potassium-dependent ATPase subunit beta-1 … IRK-1
Matched Compound Synonyms: Potassium ion(1+) … Potassium(1+) ion … Potassium(1+) … Potassium ion(1+) … Potassium(1+) ion
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