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glutaminase 2
glutaminase 1
Proton
glutamate
symport protein
Sodium/glutamate
symport carrier
protein
UDP-N-
acetylmuramoylalanine-
-D-glutamate
ligase
glutaminase 2
glutaminase 1
Glutamine
synthetase
Glutamate
racemase
UDP-N-
acetylmuramate-
-L-alanine
ligase
Glutamine
transport
ATP-binding
protein glnQ
Glutamine
transport
system permease
protein glnP
Glutamine-
binding
periplasmic
protein
Glutamate/aspartate
transport
ATP-binding
protein gltL
Glutamate/aspartate
transport
system permease
protein gltK
Glutamate/aspartate
transport
system permease
protein gltJ
Glutamate/aspartate
periplasmic-
binding protein
Adenosine
tetraphosphate
UDP-N-
acetylmuraminate
UDP-N-
acetylmuramoyl-
L-alanyl-D-
glutamate
H
+
H
+
L-Glutamic acid
L-Glutamic acid
L-Glutamic acid
Na
+
Na
+
UDP-N-
acetylmuramoyl-
L-alanine
ATP
D-Glutamic acid
ADP
P
i
L-Glutamine
H
2
O
NH
3
ATP
Ammonium
H
+
ADP
P
i
D-glutamine
H
2
O
NH
3
ATP
L-Alanine
ADP
P
i
L-Glutamine
ATP
H
2
O
ADP
P
i
H
+
ATP
H
2
O
L-Glutamic acid
ADP
H
+
P
i
Amino Sugar and
Nucleotide
Sugar
Metabolism I
Peptidoglycan
Biosynthesis I
glsB
glsA
gltP
gltS
murD
glsB
glsA
glnA
murI
murC
glnQ
glnP
glnH
gltL
gltK
gltJ
gltI
Adenosine
tetraphosphate
UDP-N-
acetylmuraminate
UDP-N-
acetylmuramoyl-
L-alanyl-D-
glutamate
Hydrogen Ion
Hydrogen Ion
L-Glutamic acid
L-Glutamic acid
L-Glutamic acid
Sodium
Sodium
UDP-N-
acetylmuramoyl-
L-alanine
Adenosine
triphosphate
D-Glutamic acid
Adenosine
diphosphate
Phosphate
L-Glutamine
Water
Ammonia
Adenosine
triphosphate
Ammonium
Hydrogen Ion
Adenosine
diphosphate
Phosphate
D-glutamine
Water
Ammonia
Adenosine
triphosphate
L-Alanine
Adenosine
diphosphate
Phosphate
L-Glutamine
Adenosine
triphosphate
Water
Adenosine
diphosphate
Phosphate
Hydrogen Ion
Adenosine
triphosphate
Water
L-Glutamic acid
Adenosine
diphosphate
Hydrogen Ion
Phosphate
Amino Sugar and
Nucleotide
Sugar
Metabolism I
Peptidoglycan
Biosynthesis I
glsB
glsA
gltP
gltS
murD
glsB
glsA
glnA
murI
murC
glnQ
glnP
glnH
gltL
gltK
gltJ
gltI
AP4
UDP-N-A
UNALADG
H
+
H
+
Glu
Glu
Glu
Na
+
Na
+
UNAL-al