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1-deoxy-D-
xylulose-5-
phosphate
synthase
1-deoxy-D-
xylulose
5-phosphate
reductoisomerase
2-C-methyl-D-
erythritol
4-phosphate
cytidylyltransferase
4-
diphosphocytidyl-
2-C-methyl-D-
erythritol
kinase
2-C-methyl-D-
erythritol 2,4-
cyclodiphosphate
synthase
4-hydroxy-3-
methylbut-2-
en-1-yl
diphosphate
synthase
4-hydroxy-3-
methylbut-2-
enyl
diphosphate
reductase
Isopentenyl-
diphosphate
Delta-isomerase
Geranyltranstransferase
Geranyltranstransferase
Ditrans,polycis-
undecaprenyl-
diphosphate
synthase
((2E,6E)-
farnesyl-
diphosphate
specific)
Octaprenyl-
diphosphate
synthase
4-hydroxy-3-
methylbut-2-
enyl
diphosphate
reductase
D-
Glyceraldehyde
3-phosphate
Farnesyl
pyrophosphate
di- trans,octa-
cis-
undecaprenyl
diphosphate
Octaprenyl
diphosphate
H
+
CO
2
1-Deoxy-D-
xylulose
5-phosphate
NADPH
H
+
NADP
2-C-methyl-D-
erythritol
4-phosphate
Cytidine
triphosphate
H
+
PP
i
4-(cytidine 5'-
diphospho)-2-
C-methyl-D-
erythritol
ATP
ADP
H
+
2-phospho-4-
(cytidine 5'-
diphospho)-2-
C-methyl-D-
erythritol
Cytidine
monophosphate
2-C-Methyl-D-
erythritol-
2,4-
cyclodiphosphate
H
2
O
H
+
1-hydroxy-2-
methyl-2-(E)-
butenyl
4-diphosphate
H
+
NADPH
H
2
O
NADPH
Isopentenyl
pyrophosphate
Dimethylallylpyrophosphate
Isopentenyl
pyrophosphate
PP
i
Geranyl-PP
Isopentenyl
pyrophosphate
PP
i
Isopentenyl
pyrophosphate
PP
i
Isopentenyl
pyrophosphate
PP
i
H
+
NADPH
NADP
H
2
O
Manganese
NADPH
Magnesium
Magnesium
Manganese
4Fe-4S
Manganese
Cobalt
FAD
NADH
NADPH
Magnesium
Zinc (II) ion
Magnesium
Magnesium
Magnesium
Magnesium
Cobalt
FAD
NADH
NADPH
a reduced
flavodoxin
an oxidized
flavodoxin
Glycolysis and
Pyruvate
Dehydrogenase
Secondary
Metabolites:
Ubiquinol
Biosynthesis
Secondary
Metabolites:
Enterobacterial
Common Antigen
Biosynthesis
Peptidoglycan
Biosynthesis I
Secondary
Metabolites:
Ubiquinol
Biosynthesis
dxs
dxr
ispD
ispE
ispF
ispG
ispH
idi
ispA
ispA
ispU
ispB
ispH
D-
Glyceraldehyde
3-phosphate
Farnesyl
pyrophosphate
di- trans,octa-
cis-
undecaprenyl
diphosphate
Octaprenyl
diphosphate
Hydrogen Ion
Carbon dioxide
1-Deoxy-D-
xylulose
5-phosphate
NADPH
Hydrogen Ion
NADP
2-C-methyl-D-
erythritol
4-phosphate
Cytidine
triphosphate
Hydrogen Ion
Pyrophosphate
4-(cytidine 5'-
diphospho)-2-
C-methyl-D-
erythritol
Adenosine
triphosphate
Adenosine
diphosphate
Hydrogen Ion
2-phospho-4-
(cytidine 5'-
diphospho)-2-
C-methyl-D-
erythritol
Cytidine
monophosphate
2-C-Methyl-D-
erythritol-
2,4-
cyclodiphosphate
Water
Hydrogen Ion
1-hydroxy-2-
methyl-2-(E)-
butenyl
4-diphosphate
Hydrogen Ion
NADPH
Water
NADPH
Isopentenyl
pyrophosphate
Dimethylallylpyrophosphate
Isopentenyl
pyrophosphate
Pyrophosphate
Geranyl-PP
Isopentenyl
pyrophosphate
Pyrophosphate
Isopentenyl
pyrophosphate
Pyrophosphate
Isopentenyl
pyrophosphate
Pyrophosphate
Hydrogen Ion
NADPH
NADP
Water
a reduced
flavodoxin
an oxidized
flavodoxin
Glycolysis and
Pyruvate
Dehydrogenase
Secondary
Metabolites:
Ubiquinol
Biosynthesis
Secondary
Metabolites:
Enterobacterial
Common Antigen
Biosynthesis
Peptidoglycan
Biosynthesis I
Secondary
Metabolites:
Ubiquinol
Biosynthesis