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Histone-lysine N- methyltransferase SETD7 Trimethyllysine dioxygenase, mitochondrial Serine hydroxymethyltransferase, cytosolic 4- trimethylaminobutyraldehyde dehydrogenase Trimethyllysine dioxygenase, mitochondrial N6,N6,N6-Trimethyl-L-lysine N6,N6,N6-Trimethyl-L-lysine 4-Trimethylammoniobutanoic acid 4-Trimethylammoniobutanoic acid L-Lysine S-Adenosylmethionine S-Adenosylhomocysteine Oxoglutaric acid O2 3-Hydroxy-N6,N6,N6- trimethyl-L-lysine Succinic acid CO2 Glycine 4-Trimethylammoniobutanal NAD H2O NADH H+ Oxoglutaric acid O2 L-Carnitine Succinic acid CO2 Fe2+ Pyridoxal 5'-phosphate Fe2+ Ascorbic acid Protein containing a lysine residue Protein containing a lysine residue Protein degradation Nucleus Nuclear Membrane Nucleoplasm Extacellular Space Intracellular Space Intracellular Space Mitochondria Liver Kidney
Nucleus SETD7 TMLHE SHMT1 ALDH9A1 TMLHE N6,N6,N6- Trimethyl-L- lysine N6,N6,N6- Trimethyl-L- lysine 4- Trimethylammoniobutanoic acid 4- Trimethylammoniobutanoic acid L-Lysine S- Adenosylmethionine S- Adenosylhomocysteine Oxoglutaric acid Oxygen 3-Hydroxy- N6,N6,N6- trimethyl-L- lysine Succinic acid Carbon dioxide Glycine 4- Trimethylammoniobutanal NAD Water NADH Hydrogen Ion Oxoglutaric acid Oxygen L-Carnitine Succinic acid Carbon dioxide Protein containing a lysine residue Protein containing a lysine residue Protein degradation
SETD7 TMLHE SHMT1 ALDH9A1 TMLHE TML-Lys TML-Lys 4-TMaba 4-TMaba Lys SAMe SAH AKG O2 3HNNNTL Succini CO2 Gly 4-TMAmB NAD H2O NADH H+ AKG O2 L-Carnt Succini CO2 Fe2+ Pyr-5'P Fe2+ VitC PCALR PCALR Pro deg Nucleus Nuclear Membrane Nucleoplasm Extacellular Space Intracellular Space Intracellular Space Mitochondria Liver Kidney