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Adenylate cyclase type 2 Guanine nucleotide- binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide- binding protein G(s) subunit alpha isoforms short Guanine nucleotide- binding protein G(I)/G(S)/G(T) subunit beta-1 Bcl2-associated agonist of cell death Adenosine receptor A2a Nuclear factor NF-kappa-B p105 subunit Nuclear factor NF-kappa-B p105 subunit Nuclear factor NF-kappa-B p105 subunit Nuclear factor NF-kappa-B p105 subunit Adenosine receptor A2a Adenosine receptor A2a Guanine nucleotide- binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide- binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide- binding protein G(s) subunit alpha isoforms short Guanine nucleotide- binding protein G(s) subunit alpha isoforms short Guanine nucleotide- binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide- binding protein G(I)/G(S)/G(T) subunit beta-1 Adenylate cyclase type 2 Guanine nucleotide- binding protein G(s) subunit alpha isoforms short cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit beta Cyclic AMP-responsive element-binding protein 1 Cyclic AMP-responsive element-binding protein 1 Rap guanine nucleotide exchange factor 3 Ras-related protein Rap-1A Ras-related protein Rap-1A Rap guanine nucleotide exchange factor 3 Dual specificity mitogen- activated protein kinase kinase 2 Dual specificity mitogen- activated protein kinase kinase 2 Ras-related protein Rap-1A RAF proto-oncogene serine/threonine- protein kinase RAF proto-oncogene serine/threonine- protein kinase Dual specificity mitogen- activated protein kinase kinase 2 Dual specificity mitogen- activated protein kinase kinase 2 Mitogen- activated protein kinase 1 Mitogen- activated protein kinase 1 ETS domain- containing protein Elk-1 ETS domain- containing protein Elk-1 Rap guanine nucleotide exchange factor 2 Rap guanine nucleotide exchange factor 2 GTPase HRas GTPase HRas Phosphatidylinositol 4,5- bisphosphate 3-kinase catalytic subunit alpha isoform GTPase HRas Phosphatidylinositol 4,5- bisphosphate 3-kinase catalytic subunit alpha isoform Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 7 Cell division control protein 42 homolog Cell division control protein 42 homolog Serine/threonine- protein kinase PAK 3 Serine/threonine- protein kinase PAK 3 Cell division control protein 42 homolog Mitogen- activated protein kinase kinase kinase 1 Mitogen- activated protein kinase kinase kinase 1 Dual specificity mitogen- activated protein kinase kinase 7 Dual specificity mitogen- activated protein kinase kinase 7 Mitogen- activated protein kinase 8 Mitogen- activated protein kinase 8 Transcription factor AP-1 Transcription factor AP-1 Cell division control protein 42 homolog Serine/threonine- protein kinase PAK 1 Serine/threonine- protein kinase PAK 1 Dual specificity mitogen- activated protein kinase kinase 7 Dual specificity mitogen- activated protein kinase kinase 7 Mitogen- activated protein kinase 14 Mitogen- activated protein kinase 14 Cyclic AMP-dependent transcription factor ATF-2 Cyclic AMP-dependent transcription factor ATF-2 Partitioning defective 6 homolog alpha Protein kinase C zeta type Cell division control protein 42 homolog Partitioning defective 6 homolog alpha Protein kinase C zeta type Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-1 Bcl2-associated agonist of cell death 3- phosphoinositide- dependent protein kinase 1 3- phosphoinositide- dependent protein kinase 1 RAC-alpha serine/threonine- protein kinase RAC-alpha serine/threonine- protein kinase RAC-alpha serine/threonine- protein kinase Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B inhibitor alpha NF-kappa-B inhibitor alpha NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Nuclear factor NF-kappa-B p105 subunit cAMP Adenosine Adenosine GTP GDP Adenosine triphosphate PPi cAMP Pi GTP GDP Pi Pi Pi GTP GDP PIP2(16:0/16:0) PIP3(16:0/16:0) GTP GDP Pi Pi Pi Pi Pi Pi Pi PIP3(16:0/16:0) Pi Pi PIP3(16:0/16:0) PIP3(16:0/16:0) PIP3(16:0/16:0) Pi Pi Pi GDP GDP GTP GTP GTP GTP GDP Magnesium Magnesium Magnesium Zinc Zinc Magnesium Magnesium cAMP Guanosine diphosphate Guanosine triphosphate Guanosine triphosphate Phosphate Guanosine diphosphate Guanosine triphosphate Magnesium Magnesium Guanosine triphosphate Magnesium Magnesium Magnesium Magnesium Magnesium Magnesium Guanosine triphosphate Magnesium Magnesium Magnesium Magnesium Magnesium Magnesium Guanosine triphosphate Regulation of glutamate and Dopamine release in the brain Coronary Artery Vasodilation in the heart Apoptosis Regulatory Subunit Regulatory Subunit Regulatory Subunit Regulatory Subunit Transcription Transcription Transcription Transcription Inhibition Transcription Nucleus Activation Activation Activation Activation Extracellular Space Intracellular Space
Adcy2 Gng7 Gnas Gnb1 Bad Adora2a Nfkb1 Nfkb1 Nfkb1 Nfkb1 Adora2a Adora2a Gng7 Gnb1 Gnas Gnas Gng7 Gnb1 Adcy2 Gnas Prkacb Prkacb Creb1 Creb1 Rapgef3 Rap1a Rap1a Rapgef3 Map2k2 Map2k2 Rap1a Raf1 Raf1 Map2k2 Map2k2 Mapk1 Mapk1 Elk1 Elk1 Rapgef2 Rapgef2 Hras Hras Pik3ca Hras Pik3ca Arhgef7 Arhgef7 Cdc42 Cdc42 Pak3 Pak3 Cdc42 Map3k1 Map3k1 Map2k7 Map2k7 Mapk8 Mapk8 Jun Jun Cdc42 Pak1 Pak1 Map2k7 Map2k7 Mapk14 Mapk14 Atf2 Atf2 Pard6a Prkcz Cdc42 Pard6a Prkcz Rps6ka1 Rps6ka1 Bad Pdpk1 Pdpk1 Akt1 Akt1 Akt1 Ikbkb Ikbkb Ikbkb Ikbkb Nfkbia Nfkbia Nfkbia Nfkb1 Nfkb1 cAMP Adenosine Adenosine Guanosine triphosphate Guanosine diphosphate Adenosine triphosphate Pyrophosphate cAMP Phosphate Guanosine triphosphate Guanosine diphosphate Phosphate Phosphate Phosphate Guanosine triphosphate Guanosine diphosphate PIP2(16:0/16:0) PIP3(16:0/16:0) Guanosine triphosphate Guanosine diphosphate Phosphate Phosphate Phosphate Phosphate Phosphate Phosphate Phosphate PIP3(16:0/16:0) Phosphate Phosphate PIP3(16:0/16:0) PIP3(16:0/16:0) PIP3(16:0/16:0) Phosphate Phosphate Phosphate Guanosine diphosphate Guanosine diphosphate Guanosine triphosphate Guanosine triphosphate Guanosine triphosphate Guanosine triphosphate Guanosine diphosphate Regulation of glutamate and Dopamine release in the brain Coronary Artery Vasodilation in the heart Apoptosis
Adcy2 Gng7 Gnas Gnb1 Bad Adora2a Nfkb1 Nfkb1 Nfkb1 Nfkb1 Adora2a Adora2a Gng7 Gnb1 Gnas Gnas Gng7 Gnb1 Adcy2 Gnas Prkacb Prkacb Creb1 Creb1 Rapgef3 Rap1a Rap1a Rapgef3 Map2k2 Map2k2 Rap1a Raf1 Raf1 Map2k2 Map2k2 Mapk1 Mapk1 Elk1 Elk1 Rapgef2 Rapgef2 Hras Hras Pik3ca Hras Pik3ca Arhgef7 Arhgef7 Cdc42 Cdc42 Pak3 Pak3 Cdc42 Map3k1 Map3k1 Map2k7 Map2k7 Mapk8 Mapk8 Jun Jun Cdc42 Pak1 Pak1 Map2k7 Map2k7 Mapk14 Mapk14 Atf2 Atf2 Pard6a Prkcz Cdc42 Pard6a Prkcz Rps6ka1 Rps6ka1 Bad Pdpk1 Pdpk1 Akt1 Akt1 Akt1 Ikbkb Ikbkb Ikbkb Ikbkb Nfkbia Nfkbia Nfkbia Nfkb1 Nfkb1 cAMP Adenosi Adenosi GTP GDP ATP PPi cAMP Pi GTP GDP Pi Pi Pi GTP GDP PIP216 PIP316 GTP GDP Pi Pi Pi Pi Pi Pi Pi PIP316 Pi Pi PIP316 PIP316 PIP316 Pi Pi Pi GDP GDP GTP GTP GTP GTP GDP Mg2+ Mg2+ Mg2+ Zinc Zinc Mg2+ Mg2+ cAMP GDP GTP GTP Pi GDP GTP Mg2+ Mg2+ GTP Mg2+ Mg2+ Mg2+ Mg2+ Mg2+ Mg2+ GTP Mg2+ Mg2+ Mg2+ Mg2+ Mg2+ Mg2+ GTP R o g a C A V i Apopt Regulatory Subunit Regulatory Subunit Regulatory Subunit Regulatory Subunit Transcription Transcription Transcription Transcription Inhibition Transcription Nucleus Activation Activation Activation Activation Extracellular Space Intracellular Space
Adcy2 Gng7 Gnas Gnb1 Bad Adora2a Nfkb1 Nfkb1 Nfkb1 Nfkb1 Adora2a Adora2a Gng7 Gnb1 Gnas Gnas Gng7 Gnb1 Adcy2 Gnas Prkacb Prkacb Creb1 Creb1 Rapgef3 Rap1a Rap1a Rapgef3 Map2k2 Map2k2 Rap1a Raf1 Raf1 Map2k2 Map2k2 Mapk1 Mapk1 Elk1 Elk1 Rapgef2 Rapgef2 Hras Hras Pik3ca Hras Pik3ca Arhgef7 Arhgef7 Cdc42 Cdc42 Pak3 Pak3 Cdc42 Map3k1 Map3k1 Map2k7 Map2k7 Mapk8 Mapk8 Jun Jun Cdc42 Pak1 Pak1 Map2k7 Map2k7 Mapk14 Mapk14 Atf2 Atf2 Pard6a Prkcz Cdc42 Pard6a Prkcz Rps6ka1 Rps6ka1 Bad Pdpk1 Pdpk1 Akt1 Akt1 Akt1 Ikbkb Ikbkb Ikbkb Ikbkb Nfkbia Nfkbia Nfkbia Nfkb1 Nfkb1 cAMP Adenosi Adenosi GTP GDP ATP Ppi cAMP Pi GTP GDP Pi Pi Pi GTP GDP PIP216 PIP316 GTP GDP Pi Pi Pi Pi Pi Pi Pi PIP316 Pi Pi PIP316 PIP316 PIP316 Pi Pi Pi GDP GDP GTP GTP GTP GTP GDP R o g a C A V i Apopt