PathBank

Pathway Description

NAD Phosphorylation and Dephosphorylation

Pseudomonas aeruginosa

Category:

Metabolite Pathway

Sub-Category:

Metabolic

Created: 2019-08-12

Last Updated: 2019-08-16

NAD kinase is required for converting NAD to NADP in various organisms such as groups of archaea, eubacteria and eukaryotes. For example, NAD kinase has shown its important role for the growth in Salmonella enterica and the importance in E.coli. NADP can be converted back to NAD via facilitation of alkaline phosphatase with water (hydroxylation).

References

NAD Phosphorylation and Dephosphorylation References

Stover CK, Pham XQ, Erwin AL, Mizoguchi SD, Warrener P, Hickey MJ, Brinkman FS, Hufnagle WO, Kowalik DJ, Lagrou M, Garber RL, Goltry L, Tolentino E, Westbrock-Wadman S, Yuan Y, Brody LL, Coulter SN, Folger KR, Kas A, Larbig K, Lim R, Smith K, Spencer D, Wong GK, Wu Z, Paulsen IT, Reizer J, Saier MH, Hancock RE, Lory S, Olson MV: Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature. 2000 Aug 31;406(6799):959-64. doi: 10.1038/35023079.

Pubmed: 10984043

Tan AS, Worobec EA: Isolation and characterization of two immunochemically distinct alkaline phosphatases from Pseudomonas aeruginosa. FEMS Microbiol Lett. 1993 Feb 1;106(3):281-6. doi: 10.1111/j.1574-6968.1993.tb05977.x.

Pubmed: 8454193

Yan J, Deforet M, Boyle KE, Rahman R, Liang R, Okegbe C, Dietrich LEP, Qiu W, Xavier JB: Bow-tie signaling in c-di-GMP: Machine learning in a simple biochemical network. PLoS Comput Biol. 2017 Aug 2;13(8):e1005677. doi: 10.1371/journal.pcbi.1005677. eCollection 2017 Aug.

Pubmed: 28767643

This pathway was propagated using PathWhiz - Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.

Propagated from SMP0002093

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