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Phenylalanine
4-monooxygenase
Aromatic-L-
amino-acid
decarboxylase
Monoamine
oxidase
4-
hydroxyphenylpyruvate
dioxygenase
Aldehyde
dehydrogenase
L-Tyrosine
ortho-
Hydroxyphenylacetic
acid
L-Phenylalanine
O
2
Tetrahydropteridine
4a-Hydroxy-
5,6,7,8-
tetrahydropteridine
Oxoglutaric
acid
Phenylpyruvic acid
L-Glutamic acid
Phenylethylamine
CO
2
O
2
H
2
O
Phenylacetaldehyde
NH
3
H
2
O
2
O
2
CO
2
NAD
H
2
O
Phenylacetic acid
NADH
H
+
Fe2+
Pyridoxal
5'-phosphate
Endoplasmic Reticulum
Membrane
Tyrosine
Metabolism
Styrene
Degradation
Phenylalanine,
Tyrosine and
Tryptophan
Biosynthesis
Tyrosine,
Piperidine and
Pyridine
Alkaloid
Biosynthesis
Tyrosine
aminotransferase
Glutamate
oxaloacetate
transaminase 1,
isoform A
Pyridoxal
5'-phosphate
Fe2+
Liver Cell
Cytoplasm
Endoplasmic Reticulum
Hn
Ddc
shps
Hpd
Aldh-III
L-Tyrosine
ortho-
Hydroxyphenylacetic
acid
L-Phenylalanine
Oxygen
Tetrahydropteridine
4a-Hydroxy-
5,6,7,8-
tetrahydropteridine
Oxoglutaric
acid
Phenylpyruvic
acid
L-Glutamic acid
Phenylethylamine
Carbon dioxide
Oxygen
Water
Phenylacetaldehyde
Ammonia
Hydrogen
peroxide
Oxygen
Carbon dioxide
NAD
Water
Phenylacetic
acid
NADH
Hydrogen Ion
Tyrosine
Metabolism
Styrene
Degradation
Phenylalanine,
Tyrosine and
Tryptophan
Biosynthesis
Tyrosine,
Piperidine and
Pyridine
Alkaloid
Biosynthesis
Dmel\CG1461
Got1
Hn
Ddc
shps
Hpd
Aldh-
III
Tyr
2-Hpaa
Phe
O
2
Thp
4-H-5-t
AKG
Ppyr
Glu
Phenam
CO
2
O
2
H
2
O
Phenyla
NH
3
H
2
O
2
O
2
CO
2
NAD
H
2
O
PAA
NADH
H
+
Fe2+
Pyr-5'P
Endoplasmic Reticulum
Membrane
Tyr Met
Sty Deg
P T a T
T P a P
Dmel\CG1461
Got1
Pyr-5'P
Fe2+
Liver Cell
Cytoplasm