PathBank

Pathway Description

Trehalose Degradation I (Low Osmolarity)

Subdoligranulum variabile DSM 15176

Category:

Metabolite Pathway

Sub-Category:

Metabolic

Created: 2024-11-09

Last Updated: 2025-06-01

In E.coli, trehalose can be only synthesized with high osmolarity, and if the osmolarity is low, then the source of trehalose can be only obtained from external via transportation with trehalose PTS permease. However, sugar can be degraded with both low or high osmolarity in E.coli. Glucokinase can phosphorylate free gluocose into glucose-6-phosphate and both glucose-6-phosphate moieties enter glycolysis.

References

Trehalose Degradation I (Low Osmolarity) References

This pathway was propagated using PathWhiz - Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.

Propagated from SMP0002109

Enter relative concentration values (without units). Elements will be highlighted in a color gradient where red = lowest concentration and green = highest concentration. For the best results, view the pathway in Black and White.

Visualize Compound Data

		Adenosine diphosphate
		Adenosine triphosphate
		Glucose 6-phosphate
		Hydrogen Ion
		Water
		α,α-trehalose
		α,α-Trehalose 6-phosphate
		β-D-Glucopyranuronic acid
		β-D-Glucose 6-phosphate

Visualize Protein Data

		Alpha amylase, catalytic domain protein
		Phosphocarrier protein HPr
		PTS system, glucose-like IIB component
		Putative PTS system sucrose-specific IIBC component
		Unknown